Evaluation of [68Ga]Ga-PSMA PET/CT images acquired with a reduced scan time duration in prostate cancer patients using the digital biograph vision

  1. Weber, Manuel Maria ORCID logo
  2. Jentzen, Walter
  3. Hofferber, Regina
  4. Herrmann, Ken
  5. Fendler, Wolfgang Peter
  6. Conti, Maurizio
  7. Wetter, Axel
  8. Kersting, David
  9. Rischpler, Christoph
  10. Fragoso Costa, Pedro

Download
s13550-021-00765-y.pdf 2,01MB
WeightNameValue
1000 Titel
  • Evaluation of [68Ga]Ga-PSMA PET/CT images acquired with a reduced scan time duration in prostate cancer patients using the digital biograph vision
1000 Autor/in
  1. Weber, Manuel Maria |
  2. Jentzen, Walter |
  3. Hofferber, Regina |
  4. Herrmann, Ken |
  5. Fendler, Wolfgang Peter |
  6. Conti, Maurizio |
  7. Wetter, Axel |
  8. Kersting, David |
  9. Rischpler, Christoph |
  10. Fragoso Costa, Pedro |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-02-28
1000 Erschienen in
1000 Quellenangabe
  • 11(1):21
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13550-021-00765-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914332/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Aim!#![!##!Methods!#!Twenty prostate cancer patients (11 for biochemical recurrence, 5 for initial staging, 4 for metastatic disease) sequentially underwent [!##!Results!#!Overall, 98% of regions (91% of affected regions) were correctly classified in the reduced acquisition protocol independent of the image reconstruction algorithm. Two nodal lesions (each ≤ 4 mm) were not identified (leading to downstaging in 1/20 cases). Mean absolute percentage deviation of SUVmax (SUVpeak) was approximately 9% (6%) for each reconstruction algorithm. The mean image noise increased from 13 to 21% (4 iterations) and from 10 to 15% (2 iterations) for PSF + TOF and TOF images.!##!Conclusions!#!High agreement at 3.5-fold reduction of scan time in terms of per-region detection (98% of regions) and image quantification (mean deviation ≤ 10%) was demonstrated; however, small lesions can be missed in about 10% of patients leading to downstaging (T1N0M0 instead of T1N1M0) in 5% of patients. Our results suggest that a reduction of scan time duration or administered [
1000 Sacherschließung
lokal PET/CT
lokal PSMA Targeted Imaging and Therapy: Prostate and Other Cancers
lokal Original Research
lokal Image quality
lokal PSMA
lokal Silicon photomultiplier
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-9000-1319|https://frl.publisso.de/adhoc/uri/SmVudHplbiwgV2FsdGVy|https://frl.publisso.de/adhoc/uri/SG9mZmVyYmVyLCBSZWdpbmE=|https://frl.publisso.de/adhoc/uri/SGVycm1hbm4sIEtlbg==|https://frl.publisso.de/adhoc/uri/RmVuZGxlciwgV29sZmdhbmcgUGV0ZXI=|https://frl.publisso.de/adhoc/uri/Q29udGksIE1hdXJpemlv|https://frl.publisso.de/adhoc/uri/V2V0dGVyLCBBeGVs|https://frl.publisso.de/adhoc/uri/S2Vyc3RpbmcsIERhdmlk|https://frl.publisso.de/adhoc/uri/UmlzY2hwbGVyLCBDaHJpc3RvcGg=|https://frl.publisso.de/adhoc/uri/RnJhZ29zbyBDb3N0YSwgUGVkcm8=
1000 Hinweis
  • DeepGreen-ID: e265cec1b86044c99e8b7a64ecb52a83 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Dateien
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6442286.rdf
1000 Erstellt am 2023-04-26T13:47:12.295+0200
1000 Erstellt von 322
1000 beschreibt frl:6442286
1000 Zuletzt bearbeitet 2023-10-19T12:16:04.167+0200
1000 Objekt bearb. Thu Oct 19 12:16:04 CEST 2023
1000 Vgl. frl:6442286
1000 Oai Id
  1. oai:frl.publisso.de:frl:6442286 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source