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1000 Titel
  • Bone metabolism is a key factor for clinical outcome of tibial plateau fractures
1000 Autor/in
  1. Krause, Matthias |
  2. Alm, Lena |
  3. Berninger, Markus |
  4. Domnick, Christoph |
  5. Fehske, Kai |
  6. Frosch, Karl-Heinz |
  7. Herbst, Elmar |
  8. Korthaus, Alexander |
  9. Raschke, Michael |
  10. Hoffmann, Reinhard |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-11-05
1000 Erschienen in
1000 Quellenangabe
  • 46(6):1227-1237
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00068-020-01537-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691299/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Given that tibial plateau fractures (TPF) are rare, they may pose a challenge to the treating surgeon due to their variety of complex fracture patterns. Numerous studies have identified potential fracture-specific, surgery-related, and patient-related risk factors for impaired patient outcomes. However, reports on the influence of bone metabolism on functional outcomes are missing.!##!Methods!#!In a retrospective multicenter cohort study, 122 TPF of 121 patients were analyzed with respect to radiological and clinical outcomes (Rasmussen) with a mean follow-up of 35.7 ± 24.9 months. The risk factor assessment included bone metabolism-affecting comorbidities and medication.!##!Results!#!The findings showed that 95.9% of the patients reported a good-to-excellent clinical outcome, and 97.4% reported a good-to-excellent radiological outcome. Logistic regression revealed that potentially impaired bone metabolism (IBM) was an independent risk factor for the clinical (p = 0.016) but not the radiological outcome (Table 4). Patients with 41-type B fractures and a potential IBM had a seven times higher risk to present a fair-to-poor clinical outcome [OR 7.45, 95 CI (4.30, 12.92)]. The most common objective impairment was a limited range of motion in 16.4% of the patients, especially in 41-type C fractures (p = 0.06). The individual failure analysis additionally identified surgery-related options for improvement.!##!Conclusion!#!This study demonstrated that potential IBM was an independent risk factor for a poor-to-fair clinical outcome.
1000 Sacherschließung
lokal Bone metabolism
lokal Female [MeSH]
lokal Recovery of Function [MeSH]
lokal Knee Joint/diagnostic imaging [MeSH]
lokal Tibial Fractures/surgery [MeSH]
lokal Adult [MeSH]
lokal Failure analysis
lokal Humans [MeSH]
lokal Knee Joint/surgery [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Risk Factors [MeSH]
lokal Tibial Fractures/diagnostic imaging [MeSH]
lokal Original Article
lokal Tibial plateau fracture
lokal Ten-segment classification
lokal Male [MeSH]
lokal Follow-up
lokal Range of Motion, Articular [MeSH]
lokal Fracture Fixation, Internal/methods [MeSH]
lokal Tibial Fractures/metabolism [MeSH]
lokal Fracture Healing [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-7345-6506|https://frl.publisso.de/adhoc/uri/QWxtLCBMZW5h|https://frl.publisso.de/adhoc/uri/QmVybmluZ2VyLCBNYXJrdXM=|https://frl.publisso.de/adhoc/uri/RG9tbmljaywgQ2hyaXN0b3Bo|https://frl.publisso.de/adhoc/uri/RmVoc2tlLCBLYWk=|https://frl.publisso.de/adhoc/uri/RnJvc2NoLCBLYXJsLUhlaW56|https://frl.publisso.de/adhoc/uri/SGVyYnN0LCBFbG1hcg==|https://frl.publisso.de/adhoc/uri/S29ydGhhdXMsIEFsZXhhbmRlcg==|https://frl.publisso.de/adhoc/uri/UmFzY2hrZSwgTWljaGFlbA==|https://frl.publisso.de/adhoc/uri/SG9mZm1hbm4sIFJlaW5oYXJk
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1000 Erstellt am 2023-04-26T17:09:25.971+0200
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