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1000 Titel
  • The effect of age on short-term and mid-term outcomes after thoracoscopic Ivor Lewis esophagectomy: a propensity score-matched analysis
1000 Autor/in
  1. Martin, Friederike |
  2. Kröll, Dino |
  3. Knitter, Sebastian |
  4. Hofmann, Tobias |
  5. Raakow, Jonas |
  6. Denecke, Christian |
  7. Pratschke, Johann |
  8. Biebl, Matthias |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-12-20
1000 Erschienen in
1000 Quellenangabe
  • 21(1):431
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12893-021-01435-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686649/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The number of elderly patients diagnosed with esophageal cancer rises. Current information about outcomes in elderly patients undergoing thoracoscopic Ivor Lewis esophagectomy is limited. The objective of this study was to evaluate the influence of age on short-and mid-term outcomes after thoracoscopic Ivor Lewis esophagectomy.!##!Methods!#!A retrospective review of 188 patients with esophageal cancer undergoing thoracoscopic Ivor Lewis esophagectomy between August 2014 and July 2019 was performed. Patients were divided into patients aged > 75 years (elderly group (EG), n = 37) and patients ≤ 75 years (younger group (YG), n = 151) and matched using propensity-score matching. Baseline characteristics, length of hospital stay, mortality and major postoperative complications (Clavien-Dindo ≥ grade III) were compared.!##!Results!#!After matching 74 patients remained (n = 37 in each group). Postoperatively, no significant differences in major and overall complications, intra-hospital and 30-day mortality, disease-free or overall survival up to 3 years after surgery were noted. The incidence of pulmonary complications (65% vs. 38%) and pneumonia (54% vs. 30%) was significantly higher and the median hospital length of stay (12 vs. 14 days) significantly longer in the EG versus YG.!##!Conclusion!#!Thoracoscopic Ivor Lewis esophagectomies resulted in acceptable postoperative major morbidity and mortality without compromising 3-years overall and disease-free survival in elderly compared to younger patients with esophageal cancer. However, the incidence of postoperative pulmonary complications was higher in patients aged over 75 years.
1000 Sacherschließung
lokal Outcome
lokal Aged [MeSH]
lokal Esophagectomy [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Age
lokal Ivor Lewis
lokal Disease-Free Survival [MeSH]
lokal Esophageal Neoplasms/surgery [MeSH]
lokal Research
lokal Esophageal cancer
lokal Propensity Score [MeSH]
lokal Thoracoscopic esophagectomy
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TWFydGluLCBGcmllZGVyaWtl|https://frl.publisso.de/adhoc/uri/S3LDtmxsLCBEaW5v|https://frl.publisso.de/adhoc/uri/S25pdHRlciwgU2ViYXN0aWFu|https://frl.publisso.de/adhoc/uri/SG9mbWFubiwgVG9iaWFz|https://frl.publisso.de/adhoc/uri/UmFha293LCBKb25hcw==|https://frl.publisso.de/adhoc/uri/RGVuZWNrZSwgQ2hyaXN0aWFu|https://frl.publisso.de/adhoc/uri/UHJhdHNjaGtlLCBKb2hhbm4=|https://frl.publisso.de/adhoc/uri/QmllYmwsIE1hdHRoaWFz
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1000 Erstellt am 2023-04-26T18:50:47.672+0200
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1000 Zuletzt bearbeitet Thu Oct 19 14:45:07 CEST 2023
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