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1000 Titel
  • Ectopic thyroid tissue in the iris: a case report
1000 Autor/in
  1. Siegel, Helena |
  2. Auw-Hädrich, Claudia |
  3. Werner, Martin |
  4. Reinhard, Thomas |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-08-28
1000 Erschienen in
1000 Quellenangabe
  • 21(1):314
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12886-021-02073-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403457/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Ectopic thyroid tissue in the iris, also known as a thyroid glandular epithelial choristoma of the iris, has only been described twice in the literature. In both cases it remained asymptomatic.!##!Case presentation!#!A 67-year-old female patient presented for the first time in mid-2017 with corneal endothelial decompensation, with a history of complicated cataract surgery and IStent® implantation. Slit lamp microscopy showed endothelial decompensation, pseudophakia, anterior synechiae and a whitish iris tumour adhering to the endothelium. The latter had existed since childhood. Given these findings, reduced visual acuity of hand movement perception and an intraocular pressure of 23 mmHg, we performed a keratoplasty combined with an en bloc resection of the iris tumour at 9 o'clock and sector iridectomy at the end of 2019. Histological and immunohistological examination of the iris tumour unexpectedly revealed thyroid tissue. After the procedure described above, the patient had an increase in visual acuity while the graft stayed clear and the eye showed no evidence of tumour recurrence or other complications.!##!Conclusions!#!We report a third case of ectopic thyroid tissue in the iris. Both previous cases remained asymptomatic, whereas in our case, size and location of the ectopic thyroid tissue contributed to a more complex cataract surgery resulting in endothelial decompensation. Therefore, in such cases appropriate patient information should be provided prior to cataract surgery. Furthermore, careful histological examination and examination of the thyroid is important to exclude malignant diagnoses such as a metastasis of a follicular thyroid carcinoma.
1000 Sacherschließung
lokal Female [MeSH]
lokal Endothelial decompensation
lokal Aged [MeSH]
lokal Iris Neoplasms/surgery [MeSH]
lokal Choristoma
lokal Humans [MeSH]
lokal Iris Neoplasms/diagnosis [MeSH]
lokal Iris/surgery [MeSH]
lokal Case report
lokal iris tumour
lokal Iridectomy [MeSH]
lokal Cornea and external eye diseases
lokal Keratoplasty
lokal Thyroid Dysgenesis [MeSH]
lokal Neoplasm Recurrence, Local [MeSH]
lokal Ectopic thyroid tissue
lokal Child [MeSH]
lokal Case Report
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  1. https://orcid.org/0000-0001-8523-8832|https://frl.publisso.de/adhoc/uri/QXV3LUjDpGRyaWNoLCBDbGF1ZGlh|https://frl.publisso.de/adhoc/uri/V2VybmVyLCBNYXJ0aW4=|https://frl.publisso.de/adhoc/uri/UmVpbmhhcmQsIFRob21hcw==
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  1. Ectopic thyroid tissue in the iris: a case report
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1000 Erstellt am 2023-04-27T09:35:30.739+0200
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1000 Zuletzt bearbeitet Thu Oct 19 14:54:07 CEST 2023
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