Download
s15010-021-01642-5.pdf 1,09MB
WeightNameValue
1000 Titel
  • Influence of microbiological diagnosis on the clinical course of spondylodiscitis
1000 Autor/in
  1. Stangenberg, Martin |
  2. Mende, Klaus Christian |
  3. Mohme, Malte |
  4. Krätzig, Theresa |
  5. Viezens, Lennart |
  6. Both, Anna |
  7. Rohde, Holger |
  8. Dreimann, Marc |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-12
1000 Erschienen in
1000 Quellenangabe
  • 49(5):1017-1027
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s15010-021-01642-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476479/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!This study sought to recognize differences in clinical disease manifestations of spondylodiscitis depending on the causative bacterial species.!##!Methods!#!We performed an evaluation of all spondylodiscitis cases in our clinic from 2013-2018. 211 patients were included, in whom a causative bacterial pathogen was identified in 80.6% (170/211). We collected the following data; disease complications, comorbidities, laboratory parameters, abscess occurrence, localization of the infection (cervical, thoracic, lumbar, disseminated), length of hospital stay and 30-day mortality rates depending on the causative bacterial species. Differences between bacterial detection in blood culture and intraoperative samples were also recorded.!##!Results!#!The detection rate of bacterial pathogens through intraoperative sampling was 66.3% and could be increased by the results of the blood cultures to a total of 80.6% (n = 170/211). S. aureus was the most frequently detected pathogen in blood culture and intraoperative specimens and and was isolated in a higher percentage cervically than in other locations of the spine. Bacteremic S. aureus infections were associated with an increased mortality (31.4% vs. overall mortality of 13.7%, p = 0.001), more frequently developing complications, such as shock, pneumonia, and myocardial infarction. Comorbidities, abscesses, length of stay, sex, and laboratory parameters all showed no differences depending on the bacterial species.!##!Conclusion!#!Blood culture significantly improved the diagnostic yield, thus underscoring the need for a structured diagnostic approach. MSSA spondylodiscitis was associated with increased mortality and a higher incidence of complications.
1000 Sacherschließung
lokal
lokal Female [MeSH]
lokal Spine/microbiology [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Vertebral osteomyelitis
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Risk factors
lokal Discitis/microbiology [MeSH]
lokal Staphylococcus aureus/isolation
lokal Male [MeSH]
lokal Abscess/microbiology [MeSH]
lokal Original Paper
lokal Spondylodiscitis
lokal Discitis/diagnosis [MeSH]
lokal Microbiology
lokal Osteomyelitis/microbiology [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-1232-2878|https://frl.publisso.de/adhoc/uri/TWVuZGUsIEtsYXVzIENocmlzdGlhbg==|https://frl.publisso.de/adhoc/uri/TW9obWUsIE1hbHRl|https://frl.publisso.de/adhoc/uri/S3LDpHR6aWcsIFRoZXJlc2E=|https://frl.publisso.de/adhoc/uri/VmllemVucywgTGVubmFydA==|https://frl.publisso.de/adhoc/uri/Qm90aCwgQW5uYQ==|https://frl.publisso.de/adhoc/uri/Um9oZGUsIEhvbGdlcg==|https://frl.publisso.de/adhoc/uri/RHJlaW1hbm4sIE1hcmM=
1000 Hinweis
  • DeepGreen-ID: 6497401cbf494d8ba39743d64f2d8fbb ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Dateien
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6444042.rdf
1000 Erstellt am 2023-04-27T11:47:10.250+0200
1000 Erstellt von 322
1000 beschreibt frl:6444042
1000 Zuletzt bearbeitet 2023-10-20T11:54:14.572+0200
1000 Objekt bearb. Fri Oct 20 11:54:14 CEST 2023
1000 Vgl. frl:6444042
1000 Oai Id
  1. oai:frl.publisso.de:frl:6444042 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source