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1000 Titel
  • Role of CMR Imaging in Diagnostics and Evaluation of Cardiac Involvement in Muscle Dystrophies
1000 Autor/in
  1. Blaszczyk, Edyta |
  2. Gröschel, Jan |
  3. Schulz-Menger, Jeanette |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-28
1000 Erschienen in
1000 Quellenangabe
  • 18(4):211-224
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11897-021-00521-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8342365/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose of review!#!This review aims to outline the utility of cardiac magnetic resonance (CMR) in patients with different types of muscular dystrophies for the assessment of myocardial involvement, risk stratification and in guiding therapeutic decisions.!##!Recent findings!#!In patients suffering from muscular dystrophies (MD), even mild initial dysfunction may lead to severe heart failure over a time course of years. CMR plays an increasing role in the diagnosis and clinical care of these patients, mostly due to its unique capability to precisely characterize subclinical and progressive changes in cardiac geometry, function in order to differentiate myocardial injury it allows the identification of inflammation, focal and diffuse fibrosis as well as fatty infiltration. CMR may provide additional information in addition to the physical examination, laboratory tests, ECG, and echocardiography. Further trials are needed to investigate the potential impact of CMR on the therapeutic decision-making as well as the assessment of long-term prognosis in different forms of muscular dystrophies. In addition to the basic cardiovascular evaluation, CMR can provide a robust, non-invasive technique for the evaluation of subclinical myocardial tissue injury like fat infiltration and focal and diffuse fibrosis. Furthermore, CMR has a unique capability to detect the progression of myocardial tissue damage in patients with a preserved systolic function.
1000 Sacherschließung
lokal Heart [MeSH]
lokal Cardiac involvement
lokal Heart failure
lokal Humans [MeSH]
lokal Cardiomyopathies/diagnostic imaging [MeSH]
lokal Cardiovascular magnetic resonance
lokal Heart Failure [MeSH]
lokal Fibrosis
lokal Fat
lokal Muscular dystrophy
lokal Magnetic Resonance Imaging [MeSH]
lokal Myocardium [MeSH]
lokal Imaging in Heart Failure (J. Schulz-Menger, Section Editor)
lokal Muscular Dystrophies/diagnostic imaging [MeSH]
lokal Topical Collection on Imaging in Heart Failure
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1000 Erstellt am 2023-04-27T12:56:03.431+0200
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