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1000 Titel
  • Assessment of esophagogastric junction morphology by dynamic real-time MRI: comparison of imaging features to high-resolution manometry
1000 Autor/in
  1. Biggemann, Lorenz |
  2. Uhlig, Johannes |
  3. Gliem, Nina |
  4. Al-Bourini, Omar |
  5. Wedi, Edris |
  6. Ellenrieder, Volker |
  7. Ghadimi, Michael |
  8. Uecker, Martin |
  9. Frahm, Jens |
  10. Lotz, Joachim |
  11. Hosseini, Ali Seif Amir |
  12. Streit, Ulrike |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-12-07
1000 Erschienen in
1000 Quellenangabe
  • 40(4):376-384
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11604-021-01210-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8977262/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!To assess the esophagogastric junction (EGJ) on real-time MRI and compare imaging parameters to EGJ morphology on high-resolution manometry (HRM).!##!Methods!#!A total of 105 of 117 eligible patients who underwent real-time MRI and high-resolution manometry for GERD-like symptoms between 2015 and 2018 at a single center were retrospectively evaluated (male n = 57; female n = 48; mean age 52.5 ± 15.4 years). Real-time MRI was performed at a median investigation time of 15 min (1 frame/40 ms). On HRM, EGJ morphology was assessed according to the Chicago classification of esophageal motility disorders. Real-time MRI was performed at 3 T using highly undersampled radial fast low-angle shot acquisitions with NLINV image reconstruction. A 10 mL pineapple juice bolus served as oral contrast agent at supine position. Real-time MRI films of the EGJ were acquired during swallowing events and during Valsalva maneuver. Anatomic and functional MRI parameters were compared to EGJ morphology on HRM.!##!Results!#!On HRM, n = 42 patients presented with EGJ type I (40.0%), n = 33 with EGJ type II (31.4%), and n = 30 with EGJ type III (28.6%). On real-time MRI, hiatal hernia was more common in patients with EGJ type III (66.7%) than in patients with EGJ type I (26.2%) and EGJ type II (30.3%; p < 0.001). Sliding hiatal hernia was more frequent in patients with EGJ type II (33.3%) than in patients with EGJ type III (16.7%) and EGJ type I (7.1%; p = 0.017). The mean esophagus-fundus angle of patients was 85 ± 31° at rest and increased to 101 ± 36° during Valsalva maneuver.!##!Conclusion!#!Real-time MRI is a non-invasive imaging method for assessment of the esophagogastric junction. Real-time MRI can visualize dynamic changes of the EGJ during swallowing events.
1000 Sacherschließung
lokal Female [MeSH]
lokal Aged [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Original Article
lokal Magnetic Resonance Imaging [MeSH]
lokal Male [MeSH]
lokal Real-time MRI
lokal HRM
lokal Esophagogastric Junction/diagnostic imaging [MeSH]
lokal EGJ
lokal Gastroesophageal Reflux/diagnosis [MeSH]
lokal High-resolution manometry
lokal Esophagogastric junction
lokal Manometry/methods [MeSH]
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  1. https://frl.publisso.de/adhoc/uri/QmlnZ2VtYW5uLCBMb3Jlbno=|https://frl.publisso.de/adhoc/uri/VWhsaWcsIEpvaGFubmVz|https://frl.publisso.de/adhoc/uri/R2xpZW0sIE5pbmE=|https://frl.publisso.de/adhoc/uri/QWwtQm91cmluaSwgT21hcg==|https://frl.publisso.de/adhoc/uri/V2VkaSwgRWRyaXM=|https://frl.publisso.de/adhoc/uri/RWxsZW5yaWVkZXIsIFZvbGtlcg==|https://frl.publisso.de/adhoc/uri/R2hhZGltaSwgTWljaGFlbA==|https://frl.publisso.de/adhoc/uri/VWVja2VyLCBNYXJ0aW4=|https://frl.publisso.de/adhoc/uri/RnJhaG0sIEplbnM=|https://frl.publisso.de/adhoc/uri/TG90eiwgSm9hY2hpbQ==|https://frl.publisso.de/adhoc/uri/SG9zc2VpbmksIEFsaSBTZWlmIEFtaXI=|https://frl.publisso.de/adhoc/uri/U3RyZWl0LCBVbHJpa2U=
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