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1000 Titel
  • Impact of failed ab-interno trabeculectomy (trabectome) on subsequent XEN45 gel stent implantation in pseudophakic eyes
1000 Autor/in
  1. Kiessling, D. |
  2. Rennings, C. |
  3. Hild, M. |
  4. Lappas, A. |
  5. Dietlein, T. S. |
  6. Roessler, G. F. |
  7. Widder, Randolf |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-08-07
1000 Erschienen in
1000 Quellenangabe
  • 41(12):4047-4053
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s10792-021-01977-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572817/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!To determine the impact of failed ab-interno trabeculectomy on the postoperative outcome of subsequent XEN45 gel stent (Allergan, CA, USA) implantation in pseudophakic eyes.!##!Methods!#!In this retrospective single-center study, we included 60 pseudophakic eyes from 60 participants who underwent XEN45 gel stent implantation. Thirty eyes each underwent primary stent implantation (control group) or had previously undergone a failed ab-interno trabeculectomy (trabectome group). The groups were matched at a 1:1 ratio based on the following criteria: preoperative and maximum Intraocular pressure (IOP), preoperative medication score, cup/disk-ratio, follow-up time, best-corrected visual acuity at baseline, age, and the proportion of patients classified as primary open angle glaucoma or exfoliation glaucoma. We defined a successful surgery by the following three scores: an IOP reduction > 20% and IOP at the longest follow-up < 21 mmHg (Score A) or < 18 mmHg (Score B) or IOP ≤ 15 mmHg and an IOP reduction ≥ 40% (Score C). One open conjunctival revision was allowed in all scores, and a repeat surgery was considered a failure.!##!Results!#!Following an average follow-up period of 22 ± 12 months, we observed a mean IOP reduction of 38%, from 23.5 ± 5.2-14.5 ± 5.0 mmHg. Comparative analyses between the groups did not reveal a significant difference in the postoperative IOP, postoperative medication score, side effects, revision rate, repeat surgery rate, or success rate.!##!Conclusions!#!Trabectome is a viable first-line procedure for medically uncontrolled glaucoma before filtering ab-interno microstent surgery is considered.
1000 Sacherschließung
lokal Follow-Up Studies [MeSH]
lokal Stents [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Glaucoma incisional surgery
lokal Trabeculectomy [MeSH]
lokal Microstent
lokal Original Paper
lokal MIGS
lokal Intraocular Pressure [MeSH]
lokal XEN
lokal Glaucoma, Open-Angle/surgery [MeSH]
lokal Open angle glaucoma
lokal Trabectome
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S2llc3NsaW5nLCBELg==|https://frl.publisso.de/adhoc/uri/UmVubmluZ3MsIEMu|https://frl.publisso.de/adhoc/uri/SGlsZCwgTS4=|https://frl.publisso.de/adhoc/uri/TGFwcGFzLCBBLg==|https://frl.publisso.de/adhoc/uri/RGlldGxlaW4sIFQuIFMu|https://frl.publisso.de/adhoc/uri/Um9lc3NsZXIsIEcuIEYu|https://orcid.org/0000-0001-7487-1501
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1000 Erstellt am 2023-04-27T14:52:23.260+0200
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