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1000 Titel
  • Treatment of a giant hepatic echinococcal cyst with percutaneous drainage and in vivo assessment of the protoscolicidal effect of praziquantel
1000 Autor/in
  1. Richter, Joachim |
  2. Lindner, Andreas Karl |
  3. Geisel, Dominik |
  4. Torsello, Giovanni Federico |
  5. Martinez, Gabriela Equihua |
  6. Isner, Caroline |
  7. Schürmann, Dirk |
  8. Pfäfflin, Frieder |
  9. Orhun, Arzu |
  10. Manciulli, Tommaso |
  11. Brunetti, Enrico |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-04-13
1000 Erschienen in
1000 Quellenangabe
  • 14(3):888-892
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s12328-021-01397-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154811/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Therapy choices for cystic echinococcisis (CE) are stage-specific: surgical, minimally invasive, medical or observation without intervention. PAIR (percutaneous aspiration, instillation of a scolicide, and re-aspiration) has been considered the treatment of choice for uncomplicated echinococcal liver cysts. However, PAIR carries the risk of toxic cholangitis or hypernatremia and that the cyst frequently refills with bile after withdrawing the catheter. We treated a patient with a giant CE 1 liver cyst with puncture drainage (PD) under albendazole coverage. Drainage enabled us to monitor the morphology of protoscolices under praziquantel (PZQ) co-medication. Protoscolices degenerated within 5 days of PZQ 50 mg/kg/d. The cyst cavity solidified with no evidence of reactivation or secondary spread. Percutaneous treatments can replace surgery in a significant number or cases with hepatic CE. PD allows to assess microscopically the viability of protoscolices under co-medication with PZQ-albendazole and to avoid the instillation of topical scolicides.
1000 Sacherschließung
lokal
lokal Albendazole
lokal Humans [MeSH]
lokal Drainage [MeSH]
lokal Praziquantel [MeSH]
lokal Animals [MeSH]
lokal Percutaneous drainage
lokal Cystic echinococcosis
lokal Echinococcosis, Hepatic/surgery [MeSH]
lokal Praziquantel
lokal Echinococcus [MeSH]
lokal Cysts/drug therapy [MeSH]
lokal Echinococcosis, Hepatic/drug therapy [MeSH]
lokal Case Report
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-1930-2944|https://frl.publisso.de/adhoc/uri/TGluZG5lciwgQW5kcmVhcyBLYXJs|https://frl.publisso.de/adhoc/uri/R2Vpc2VsLCBEb21pbmlr|https://frl.publisso.de/adhoc/uri/VG9yc2VsbG8sIEdpb3Zhbm5pIEZlZGVyaWNv|https://frl.publisso.de/adhoc/uri/TWFydGluZXosIEdhYnJpZWxhIEVxdWlodWE=|https://frl.publisso.de/adhoc/uri/SXNuZXIsIENhcm9saW5l|https://frl.publisso.de/adhoc/uri/U2Now7xybWFubiwgRGlyaw==|https://frl.publisso.de/adhoc/uri/UGbDpGZmbGluLCBGcmllZGVy|https://frl.publisso.de/adhoc/uri/T3JodW4sIEFyenU=|https://frl.publisso.de/adhoc/uri/TWFuY2l1bGxpLCBUb21tYXNv|https://frl.publisso.de/adhoc/uri/QnJ1bmV0dGksIEVucmljbw==
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1000 Erstellt am 2023-04-28T10:43:12.832+0200
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1000 Zuletzt bearbeitet 2023-10-20T15:49:20.810+0200
1000 Objekt bearb. Fri Oct 20 15:49:20 CEST 2023
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