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1000 Titel
  • Endoscopic Negative Pressure Therapy (ENPT) Is Superior to Stent Therapy for Staple Line Leak After Sleeve Gastrectomy: a Single-Center Cohort Study
1000 Autor/in
  1. archid, rami |
  2. Bazerbachi, Fateh |
  3. Abu Dayyeh, Barham K. |
  4. Hönes, Felix |
  5. Ahmad, Suhaib J. S. |
  6. Thiel, Karolin |
  7. Nadiradze, Giorgi |
  8. Königsrainer, Alfred |
  9. Wichmann, Dörte |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-03-01
1000 Erschienen in
1000 Quellenangabe
  • 31(6):2511-2519
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11695-021-05287-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113301/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Staple line leak (SLL) is a serious complication after sleeve gastrectomy (SG). Common endoscopic treatment options include self-expandable metallic stent (SEMS), endoscopic internal drainage (EID), and endoscopic closure. The endoscopic negative pressure therapy (ENPT) is a promising treatment option combining temporary sealing of the defect with drainage of the inflammatory bed. In this study, we compare the outcome of ENPT and SEMS for the treatment of SLL following SG.!##!Materials and methods!#!A retrospective cohort of 27 patients (21 females) treated at a single center for SLL after SG was included. ENPT was primary therapy for 14 patients and compared with 13 patients treated primarily using SEMS.!##!Results!#!ENPT was associated with a significant reduction of hospital stay (19 ± 15.1 vs. 56.69 ± 47.21 days, p = 0.027), reduced duration of endoscopic treatment (9.8 ± 8.6 vs. 44.92 ± 60.98 days, p = 0.009), and shorter transabdominal drain dwell time (15 (5-96) vs. 45 (12-162) days, p = 0.014) when compared to SEMS. Whereas endoscopic management was successful in 12/14 (85.7%) of patients from the ENPT group, SEMS was successful in only 5/13 (38.5%) of patients (p = 0.015). Furthermore, ENPT was associated with a significant reduction of endoscopic adverse events compared with SEMS (14.3% vs. 76.92% p = 0.001).!##!Conclusion!#!Compared with SEMS, ENPT is effective and safe in treating SLL after SG providing higher success rates, shorter treatment duration, and lower adverse events rates.
1000 Sacherschließung
lokal Sleeve gastrectomy
lokal Female [MeSH]
lokal Stents [MeSH]
lokal Humans [MeSH]
lokal Obesity, Morbid/surgery [MeSH]
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Original Contributions
lokal Gastrectomy/adverse effects [MeSH]
lokal Cohort Studies [MeSH]
lokal Endoscopic Vacuum therapy
lokal Surgical complications
lokal Stent
lokal Staple line leak
lokal Anastomotic Leak/etiology [MeSH]
lokal Anastomotic Leak/surgery [MeSH]
lokal Endoscopic negative pressure therapy
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-0814-7723|https://frl.publisso.de/adhoc/uri/QmF6ZXJiYWNoaSwgRmF0ZWg=|https://frl.publisso.de/adhoc/uri/QWJ1IERheXllaCwgQmFyaGFtIEsu|https://frl.publisso.de/adhoc/uri/SMO2bmVzLCBGZWxpeA==|https://frl.publisso.de/adhoc/uri/QWhtYWQsIFN1aGFpYiBKLiBTLg==|https://frl.publisso.de/adhoc/uri/VGhpZWwsIEthcm9saW4=|https://frl.publisso.de/adhoc/uri/TmFkaXJhZHplLCBHaW9yZ2k=|https://frl.publisso.de/adhoc/uri/S8O2bmlnc3JhaW5lciwgQWxmcmVk|https://frl.publisso.de/adhoc/uri/V2ljaG1hbm4sIETDtnJ0ZQ==
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1000 Erstellt am 2023-04-28T11:01:10.498+0200
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1000 Zuletzt bearbeitet Fri Oct 20 16:11:20 CEST 2023
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