Molecular Basis of Coupled Transport and Anion Conduction in Excitatory Amino Acid Transporters

  1. Alleva, Claudia
  2. Machtens, Jan-Philipp
  3. Kortzak, Daniel
  4. Weyand, Ingo
  5. Fahlke, Christoph ORCID logo

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WeightNameValue
1000 Titel
  • Molecular Basis of Coupled Transport and Anion Conduction in Excitatory Amino Acid Transporters
1000 Autor/in
  1. Alleva, Claudia |
  2. Machtens, Jan-Philipp |
  3. Kortzak, Daniel |
  4. Weyand, Ingo |
  5. Fahlke, Christoph |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-02-15
1000 Erschienen in
1000 Quellenangabe
  • 47(1):9-22
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11064-021-03252-x |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763778/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. After its release from presynaptic nerve terminals, glutamate is quickly removed from the synaptic cleft by excitatory amino acid transporters (EAATs) 1-5, a subfamily of glutamate transporters. The five proteins utilize a complex transport stoichiometry that couples glutamate transport to the symport of three Na
1000 Sacherschließung
lokal Conformational selection
lokal Glt
lokal EAAT anion channel
lokal Mammals/metabolism [MeSH]
lokal Animals [MeSH]
lokal Glutamic Acid/metabolism [MeSH]
lokal Transport stoichiometry
lokal Anions/metabolism [MeSH]
lokal Excitatory Amino Acid Transporter 1/metabolism [MeSH]
lokal Tryptophan
lokal Amino Acid Transport System X-AG/metabolism [MeSH]
lokal Induced fit
lokal Original Paper
lokal Dual function protein
lokal Glutamate Plasma Membrane Transport Proteins/metabolism [MeSH]
lokal Coupled transport
lokal Hairpin 2
lokal MD simulations
lokal Glutamate transporter
lokal Fluorescence spectroscopy
lokal Biological Transport [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QWxsZXZhLCBDbGF1ZGlh|https://frl.publisso.de/adhoc/uri/TWFjaHRlbnMsIEphbi1QaGlsaXBw|https://frl.publisso.de/adhoc/uri/S29ydHphaywgRGFuaWVs|https://frl.publisso.de/adhoc/uri/V2V5YW5kLCBJbmdv|https://orcid.org/0000-0001-8602-9952
1000 Hinweis
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1000 Erstellt am 2023-04-28T11:47:05.501+0200
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1000 Zuletzt bearbeitet Fri Oct 20 17:16:42 CEST 2023
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1000 Vgl. frl:6445961
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