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1000 Titel
  • Feasibility and suitability of a graded exercise test in patients with aggressive hemato-oncological disease
1000 Autor/in
  1. Großek, Anja |
  2. Elter, Thomas |
  3. Oberste, Max |
  4. Wolf, Florian |
  5. Joisten, Niklas |
  6. Hartig, Philipp |
  7. Walzik, David |
  8. Rosenberger, Friederike |
  9. Kiesl, David |
  10. Wahl, Patrick |
  11. Bloch, Wilhelm |
  12. Zimmer, Philipp |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-02-05
1000 Erschienen in
1000 Quellenangabe
  • 29(8):4859-4866
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00520-021-06035-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236443/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Physical activity promises to reduce disease-related symptoms and therapy-related side effects in patients suffering from aggressive lymphoma (L) or acute leukemia (AL). For an efficient training program, determination of patients' physical capacity with a purposive exercise test is crucial. Here, we evaluated the feasibility and suitability of a graded exercise test (GXT) frequently applied in patients suffering from solid tumors by assessing whether patients achieved criteria for maximal exercise testing according to the American College of Sports Medicine (ACSM).!##!Methods!#!The GXT was performed by 51 patients with an aggressive L or AL prior to the start or in the earliest possible phase of high-dose chemotherapy, following a recommended protocol for cancer patients, starting at 20 Watts (W), with an increase of 10 W/min until volitional exhaustion. Subsequently, we investigated whether the following ACSM criteria were fulfilled: (1) failure of heart rate to increase despite increasing workload, (2) post-exercise capillary lactate concentration ≥ 8.0 mmol L!##!Results!#!Out of 51 patients, two, six, and 35 participants met the first, second, and third criterion, respectively. No relevant relationships between the completion of the criteria and patients' characteristics (e.g., gender, age) were found.!##!Conclusion!#!Although results of this study suggest a general feasibility of the applied GXT, the ACSM criteria were not met by the majority of the participants. Therefore, this study raises doubts about the suitability of the GXT protocol and the ACSM criteria for this group of patients.
1000 Sacherschließung
lokal Adolescent [MeSH]
lokal Female [MeSH]
lokal Lymphoma
lokal Exercise test
lokal Aged [MeSH]
lokal Adult [MeSH]
lokal Exercise Test/methods [MeSH]
lokal Humans [MeSH]
lokal Middle Aged [MeSH]
lokal Cross-Sectional Studies [MeSH]
lokal Feasibility Studies [MeSH]
lokal Exercise/physiology [MeSH]
lokal Original Article
lokal ACSM criteria
lokal Male [MeSH]
lokal Acute leukemia
lokal Young Adult [MeSH]
lokal Hematologic Neoplasms/diagnosis [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/R3Jvw59laywgQW5qYQ==|https://frl.publisso.de/adhoc/uri/RWx0ZXIsIFRob21hcw==|https://frl.publisso.de/adhoc/uri/T2JlcnN0ZSwgTWF4|https://frl.publisso.de/adhoc/uri/V29sZiwgRmxvcmlhbg==|https://frl.publisso.de/adhoc/uri/Sm9pc3RlbiwgTmlrbGFz|https://frl.publisso.de/adhoc/uri/SGFydGlnLCBQaGlsaXBw|https://frl.publisso.de/adhoc/uri/V2FsemlrLCBEYXZpZA==|https://frl.publisso.de/adhoc/uri/Um9zZW5iZXJnZXIsIEZyaWVkZXJpa2U=|https://frl.publisso.de/adhoc/uri/S2llc2wsIERhdmlk|https://frl.publisso.de/adhoc/uri/V2FobCwgUGF0cmljaw==|https://frl.publisso.de/adhoc/uri/QmxvY2gsIFdpbGhlbG0=|https://orcid.org/0000-0001-9631-4503
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1000 Erstellt am 2023-04-28T13:49:50.276+0200
1000 Erstellt von 322
1000 beschreibt frl:6446674
1000 Zuletzt bearbeitet 2023-10-20T18:45:27.895+0200
1000 Objekt bearb. Fri Oct 20 18:45:27 CEST 2023
1000 Vgl. frl:6446674
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