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1000 Titel
  • Ligation of the middle hepatic vein to increase hypertrophy induction during the ALPPS procedure
1000 Autor/in
  1. Dondorf, Felix |
  2. Deeb, A. Ali |
  3. Bauschke, A. |
  4. Felgendreff, P. |
  5. Tautenhahn, H. M. |
  6. Ardelt, M. |
  7. Settmacher, U. |
  8. Rauchfuss, F. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-05-10
1000 Erschienen in
1000 Quellenangabe
  • 406(4):1111-1118
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00423-021-02181-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208903/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Here, we analyse the technical modification of the ALPPS procedure, ligating the middle hepatic vein during the first step of the operation to enhance remnant liver hypertrophy.!##!Methods!#!In 20 of 37 ALPPS procedures, the middle hepatic vein was ligated during the first step. Hypertrophy of the functional remnant liver volume was assessed in addition to postoperative courses.!##!Results!#!Volumetric analysis showed a significant volume increase, especially for patients with colorectal metastases. Pre-existing liver parenchyma damage (odds ratio = 0.717, p = 0.017) and preoperative chemotherapy were found to be significant predictors (odds ratio = 0.803, p = 0.045) of higher morbidity and mortality. In addition, a survival benefit for maintenance of middle hepatic vein was shown.!##!Conclusion!#!This technical modification of the ALPPS procedure can accentuate future liver remnant volume hypertrophy. The higher morbidity and mortality observed are most likely associated with pre-existing parenchymal damage within this group.
1000 Sacherschließung
lokal Hypertrophy induction
lokal Liver Regeneration [MeSH]
lokal Liver Neoplasms/surgery [MeSH]
lokal Hepatectomy [MeSH]
lokal Humans [MeSH]
lokal Ligation [MeSH]
lokal Hypertrophy [MeSH]
lokal Original Article
lokal ALPPS
lokal Hepatic Veins/surgery [MeSH]
lokal Liver/surgery [MeSH]
lokal Portal Vein/surgery [MeSH]
lokal Middle hepatic vein
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-3569-938X|https://frl.publisso.de/adhoc/uri/RGVlYiwgQS4gQWxp|https://frl.publisso.de/adhoc/uri/QmF1c2Noa2UsIEEu|https://frl.publisso.de/adhoc/uri/RmVsZ2VuZHJlZmYsIFAu|https://frl.publisso.de/adhoc/uri/VGF1dGVuaGFobiwgSC4gTS4=|https://frl.publisso.de/adhoc/uri/QXJkZWx0LCBNLg==|https://frl.publisso.de/adhoc/uri/U2V0dG1hY2hlciwgVS4=|https://frl.publisso.de/adhoc/uri/UmF1Y2hmdXNzLCBGLg==
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1000 Erstellt am 2023-04-28T14:52:12.414+0200
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1000 Zuletzt bearbeitet 2023-10-20T19:25:57.961+0200
1000 Objekt bearb. Fri Oct 20 19:25:57 CEST 2023
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