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1000 Titel
  • Long-term physical training in adolescent sprint and middle distance swimmers alters the composition of circulating T and NK cells which correlates with soluble ICAM-1 serum concentrations
1000 Autor/in
  1. Notbohm, Hannah L. |
  2. Schumann, Moritz |
  3. Fuhrmann, Stefan |
  4. Klocke, Jan |
  5. Theurich, Sebastian |
  6. Bloch, Wilhelm |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-03-11
1000 Erschienen in
1000 Quellenangabe
  • 121(6):1773-1781
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00421-021-04660-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144138/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!It remains unknown how different training intensities and volumes chronically impact circulating lymphocytes and cellular adhesion molecules. First, we aimed to monitor changes in NK and T cells over a training season and relate these to training load. Second, we analyzed effects of training differences between swimmers on these cells. Finally, we examined if changes in lymphocytes were associated with sICAM-1 concentrations.!##!Methods!#!We analyzed weekly training volume, training intensity, proportions of T and NK cells and serum sICAM-1 in eight sprint (SS) and seven middle-distance swimmers (MID) at three points over a 16-week training period: at the start (t!##!Results!#!Training volume of all swimmers was statistically higher and training intensity lower from t!##!Conclusion!#!These results indicate that intensified training in swimmers resulted in transient changes in T and NK cells. Further, NK cells are sensitive to high training volumes. Lastly, sICAM-1 concentrations may be associated with the migration and maturation of CD4
1000 Sacherschließung
lokal Adolescent [MeSH]
lokal Female [MeSH]
lokal Killer Cells, Natural/metabolism [MeSH]
lokal Training intensity distribution
lokal T-Lymphocytes/metabolism [MeSH]
lokal Cell adhesion molecules
lokal Humans [MeSH]
lokal Lymphocytes
lokal CD45RA
lokal Intercellular Adhesion Molecule-1/blood [MeSH]
lokal Physical Education and Training/methods [MeSH]
lokal Original Article
lokal Cell trafficking
lokal Male [MeSH]
lokal Immune system
lokal Swimming/physiology [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Tm90Ym9obSwgSGFubmFoIEwu|https://orcid.org/0000-0001-9605-3489|https://frl.publisso.de/adhoc/uri/RnVocm1hbm4sIFN0ZWZhbg==|https://frl.publisso.de/adhoc/uri/S2xvY2tlLCBKYW4=|https://orcid.org/0000-0001-5706-8258|https://frl.publisso.de/adhoc/uri/QmxvY2gsIFdpbGhlbG0=
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1000 Erstellt am 2023-04-28T15:06:55.356+0200
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