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1000 Titel
  • CMR feature tracking strain patterns and their association with circulating cardiac biomarkers in patients with hypertrophic cardiomyopathy
1000 Autor/in
  1. Cavus, Ersin |
  2. Muellerleile, Kai |
  3. Schellert, Samuel |
  4. Schneider, Jan |
  5. Tahir, Enver |
  6. Chevalier, Celeste |
  7. Jahnke, Charlotte |
  8. Radunski, Ulf K. |
  9. Adam, Gerhard |
  10. Kirchhof, Paulus |
  11. Blankenberg, Stefan |
  12. Lund, Gunnar K. |
  13. Avanesov, Maxim |
  14. Patten, Monica |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-03-29
1000 Erschienen in
1000 Quellenangabe
  • 110(11):1757-1769
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00392-021-01848-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563550/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Aims!#!CMR feature tracking strain (CMR-FT) provides prognostic information. However, there is a paucity of data in hypertrophic cardiomyopathy (HCM). We sought to analyze global CMR-FT parameters in all four cardiac chambers and to assess associations with NT-proBNP and cardiac troponin T (hsTnT) in patients with HCM.!##!Methods!#!This retrospective study included 144 HCM patients and 16 healthy controls with CMR at 1.5 T. Analyses were performed on standard steady-state free precession cine (SSFP) CMR data using a commercially available software. Global left ventricular (LV) strain was assessed as longitudinal (LV!##!Results!#!We found LV!##!Conclusion!#!CMR-FT reveals LV and LA dysfunction in HCM despite normal LVEF. The association between impaired LV strain and elevated NT-proBNP and hsTnT indicates a link between unapparent functional abnormalities and disease severity in HCM. Typical CMR-FT findings in patients with hypertrophic cardiomyopathy.
1000 Sacherschließung
lokal Magnetic Resonance Imaging, Cine/methods [MeSH]
lokal Heart Ventricles/physiopathology [MeSH]
lokal Myocardial Contraction/physiology [MeSH]
lokal Natriuretic Peptide, Brain/blood [MeSH]
lokal Strain imaging
lokal Stroke Volume/physiology [MeSH]
lokal Cardiomyopathy, Hypertrophic/physiopathology [MeSH]
lokal Cardiomyopathy, Hypertrophic/diagnosis [MeSH]
lokal Ventricular Function, Left/physiology [MeSH]
lokal Male [MeSH]
lokal Peptide Fragments/blood [MeSH]
lokal Female [MeSH]
lokal Cardiac biomarker
lokal Follow-Up Studies [MeSH]
lokal Adult [MeSH]
lokal Biomarkers/blood [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal CMR feature tracking strain
lokal Hypertrophic cardiomyopathy
lokal ROC Curve [MeSH]
lokal Original Paper
lokal Prognosis [MeSH]
lokal Heart Ventricles/pathology [MeSH]
lokal Cardiomyopathy, Hypertrophic/blood [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-5372-8690|https://frl.publisso.de/adhoc/uri/TXVlbGxlcmxlaWxlLCBLYWk=|https://frl.publisso.de/adhoc/uri/U2NoZWxsZXJ0LCBTYW11ZWw=|https://frl.publisso.de/adhoc/uri/U2NobmVpZGVyLCBKYW4=|https://frl.publisso.de/adhoc/uri/VGFoaXIsIEVudmVy|https://frl.publisso.de/adhoc/uri/Q2hldmFsaWVyLCBDZWxlc3Rl|https://frl.publisso.de/adhoc/uri/SmFobmtlLCBDaGFybG90dGU=|https://frl.publisso.de/adhoc/uri/UmFkdW5za2ksIFVsZiBLLg==|https://frl.publisso.de/adhoc/uri/QWRhbSwgR2VyaGFyZA==|https://frl.publisso.de/adhoc/uri/S2lyY2hob2YsIFBhdWx1cw==|https://frl.publisso.de/adhoc/uri/QmxhbmtlbmJlcmcsIFN0ZWZhbg==|https://frl.publisso.de/adhoc/uri/THVuZCwgR3VubmFyIEsu|https://frl.publisso.de/adhoc/uri/QXZhbmVzb3YsIE1heGlt|https://frl.publisso.de/adhoc/uri/UGF0dGVuLCBNb25pY2E=
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1000 Erstellt am 2023-05-03T15:41:28.200+0200
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1000 Zuletzt bearbeitet Fri Oct 20 20:47:12 CEST 2023
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