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1000 Titel
  • The good and the bad about separation anxiety: roles of IL-22 and IL-22BP in liver pathologies
1000 Autor/in
  1. Lücke, Jöran |
  2. Sabihi, Morsal |
  3. Zhang, Tao |
  4. Bauditz, Lennart Fynn |
  5. Shiri, Ahmad Mustafa |
  6. Giannou, Anastasios D. |
  7. Huber, Samuel |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-04-13
1000 Erschienen in
1000 Quellenangabe
  • 43(4):591-607
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00281-021-00854-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443499/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The human liver fulfills several vital tasks daily and possesses an impressive ability to self-regenerate. However, the capacity of this self-healing process can be exhausted by a variety of different liver diseases, such as alcoholic liver damage, viral hepatitis, or hepatocellular carcinoma. Over time, all these diseases generally lead to progressive liver failure that can become fatal if left untreated. Thus, a great effort has been directed towards the development of innovative therapies. The most recently discovered therapies often involve modifying the patient's immune system to enhance a beneficial immune response. Current data suggest that, among others, the cytokine IL-22 might be a promising therapeutical candidate. IL-22 and its endogenous antagonist, IL-22BP, have been under thorough scientific investigation for nearly 20 years. While IL-22 is mainly produced by T
1000 Sacherschließung
lokal IL-22BP
lokal Interleukins [MeSH]
lokal Liver infection
lokal Liver [MeSH]
lokal Humans [MeSH]
lokal Hepatocellular carcinoma
lokal Review
lokal Receptors, Interleukin [MeSH]
lokal IL-22
lokal Liver damage
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TMO8Y2tlLCBKw7ZyYW4=|https://frl.publisso.de/adhoc/uri/U2FiaWhpLCBNb3JzYWw=|https://frl.publisso.de/adhoc/uri/WmhhbmcsIFRhbw==|https://frl.publisso.de/adhoc/uri/QmF1ZGl0eiwgTGVubmFydCBGeW5u|https://frl.publisso.de/adhoc/uri/U2hpcmksIEFobWFkIE11c3RhZmE=|https://frl.publisso.de/adhoc/uri/R2lhbm5vdSwgQW5hc3Rhc2lvcyBELg==|https://orcid.org/0000-0001-9325-8227
1000 Hinweis
  • DeepGreen-ID: 318eb5bc501b42d8a8f6fdb2a8371cce ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-05-03T16:23:21.742+0200
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1000 Zuletzt bearbeitet 2023-10-20T21:15:32.055+0200
1000 Objekt bearb. Fri Oct 20 21:15:32 CEST 2023
1000 Vgl. frl:6447773
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