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1000 Titel
  • How can fertility counseling be implemented for every newly diagnosed pediatric patient facing gonadotoxic treatment?-A single-center experience
1000 Autor/in
  1. Barnbrock, Anke |
  2. Salzmann-Manrique, Emilia |
  3. Sänger, Nicole |
  4. Fiegel, Henning |
  5. Ochsendorf, Falk |
  6. Klingebiel, Thomas |
  7. Bader, Peter |
  8. Jarisch, Andrea |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-09-18
1000 Erschienen in
1000 Quellenangabe
  • 100(11):2831-2841
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00277-021-04648-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8510917/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Since the survival rates of pediatric patients undergoing cancer treatment or hematopoietic stem cell transplantation (HSCT) have increased rapidly in recent decades, the late effects of treatment are now an important focus of patient care. Access to fertility preservation (FP) procedures as well as their financing differs considerably across Europe. However, some countries in Europe have recently changed the legal basis for financing FP procedures; therefore, the implementation of structures is mandatory to give patients access to FP. In this prospective cohort study, we characterized the process for establishing pediatric fertility counseling, including the development of an in-house standard procedure for recommendations regarding FP with potentially gonadotoxic treatment and valuating data from all FP counseling sessions. All data concerning patient characteristics (pubertal status, disease group) and recommendation of FP measures were prospectively collected and adoption of FP measures analyzed. Prior to the establishment of a structured process for FP in our pediatric oncology and stem cell transplantation center, there was no standardized FP counseling. We demonstrate that with the establishment of an inhouse standard procedure, it is possible to give consistent yet individualized FP counseling to approximately 90% of our patients facing gonadotoxic treatment, counseling over 200 patients between 2017 and 2019. This pilot study could potentially be adapted in other pediatric hematology, oncology, and stem cell transplantation centers to allow a more standardized handling of FP counseling for all patients facing gonadotoxic treatment.
1000 Sacherschließung
lokal Antineoplastic Agents/adverse effects [MeSH]
lokal Infertility, Male/prevention
lokal Puberty [MeSH]
lokal Ovary/transplantation [MeSH]
lokal Infertility, Male/chemically induced [MeSH]
lokal Original Article
lokal Infant [MeSH]
lokal Male [MeSH]
lokal Infertility, Female/chemically induced [MeSH]
lokal Oocyte Retrieval [MeSH]
lokal Neoplasms/therapy [MeSH]
lokal Semen Preservation [MeSH]
lokal Child [MeSH]
lokal Infertility, Male/etiology [MeSH]
lokal Infertility, Female/etiology [MeSH]
lokal Adolescent [MeSH]
lokal Female [MeSH]
lokal Cryopreservation [MeSH]
lokal Humans [MeSH]
lokal Infertility, Female/prevention
lokal Prospective Studies [MeSH]
lokal Pediatric stem cell transplantation
lokal Hematopoietic Stem Cell Transplantation [MeSH]
lokal Counseling/methods [MeSH]
lokal Fertility Preservation/standards [MeSH]
lokal Fertility Preservation/methods [MeSH]
lokal Pediatric oncology
lokal Radiotherapy/adverse effects [MeSH]
lokal Fertility Preservation/economics [MeSH]
lokal Transplantation Conditioning/adverse effects [MeSH]
lokal Young Adult [MeSH]
lokal Radiation Injuries/prevention
lokal Fertility counseling
lokal Child, Preschool [MeSH]
lokal Indication for fertility preservation
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QmFybmJyb2NrLCBBbmtl|https://frl.publisso.de/adhoc/uri/U2Fsem1hbm4tTWFucmlxdWUsIEVtaWxpYQ==|https://frl.publisso.de/adhoc/uri/U8OkbmdlciwgTmljb2xl|https://frl.publisso.de/adhoc/uri/RmllZ2VsLCBIZW5uaW5n|https://frl.publisso.de/adhoc/uri/T2Noc2VuZG9yZiwgRmFsaw==|https://frl.publisso.de/adhoc/uri/S2xpbmdlYmllbCwgVGhvbWFz|https://frl.publisso.de/adhoc/uri/QmFkZXIsIFBldGVy|https://frl.publisso.de/adhoc/uri/SmFyaXNjaCwgQW5kcmVh
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1000 Erstellt am 2023-05-03T16:27:22.562+0200
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