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1000 Titel
  • Incidental findings on 3 T neuroimaging: cross-sectional observations from the population-based Rhineland Study
1000 Autor/in
  1. Lohner, Valerie |
  2. Lu, Ran |
  3. Enkirch, Simon Jonas |
  4. Stoecker, Tony |
  5. Hattingen, Elke |
  6. Breteler, Monique M.B. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-29
1000 Erschienen in
1000 Quellenangabe
  • 64(3):503-512
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00234-021-02852-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850254/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Development of best practices for dealing with incidental findings on neuroimaging requires insight in their frequency and clinical relevance.!##!Methods!#!Here, we delineate prevalence estimates with 95% confidence intervals and clinical management of incidental findings, based on the first 3589 participants of the population-based Rhineland Study (age range 30-95 years) who underwent 3 Tesla structural neuroimaging (3D, 0.8 mm!##!Results!#!Of 3589 participants (mean age 55 ± 14 years, 2072 women), 867 had at least one possible incidental finding (24.2%). Most common were pituitary abnormalities (12.3%), arachnoid cysts (4.1%), developmental venous anomalies (2.5%), non-acute infarcts (1.8%), cavernomas (1.0%), and meningiomas (0.7%). Forty-six participants were informed about their findings, which was hitherto unknown in 40 of them (1.1%). Of these, in 19 participants (48%), a wait-and-see policy was applied and nine (23%) received treatment, while lesions in the remainder were benign, could not be confirmed, or the participant refused to inform us about their clinical diagnosis.!##!Conclusion!#!Nearly one-quarter of participants had an incidental finding, but only 5% of those required referral, that mostly remained without direct clinical consequences.
1000 Sacherschließung
lokal Meningeal Neoplasms/pathology [MeSH]
lokal Female [MeSH]
lokal Brain/pathology [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Middle Aged [MeSH]
lokal Cross-Sectional Studies [MeSH]
lokal MRI
lokal Incidental Findings [MeSH]
lokal Population-based study
lokal Neuroimaging/methods [MeSH]
lokal Neuroimaging
lokal Male [MeSH]
lokal Magnetic Resonance Imaging/methods [MeSH]
lokal Incidental findings
lokal Diagnostic Neuroradiology
lokal Observational study
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-5589-9701|https://orcid.org/0000-0002-7237-3362|https://orcid.org/0000-0002-5819-0308|https://orcid.org/0000-0002-8946-9141|https://orcid.org/0000-0002-8392-9004|https://orcid.org/0000-0002-0626-9305
1000 Hinweis
  • DeepGreen-ID: 8a295a28dafb4070b69a73b28cd53fcb ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-05-03T16:52:35.774+0200
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1000 Zuletzt bearbeitet 2023-10-20T21:37:09.042+0200
1000 Objekt bearb. Fri Oct 20 21:37:09 CEST 2023
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