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1000 Titel
  • Hemodynamic evaluation of patients with Moyamoya Angiopathy: comparison of resting-state fMRI to breath-hold fMRI and [15O]water PET
1000 Autor/in
  1. Zerweck, Leonie |
  2. Roder, Constantin |
  3. Hauser, Till-Karsten |
  4. Thurow, Johannes |
  5. Mengel, Annerose |
  6. Tatagiba, Marcos |
  7. Khan, Nadia |
  8. , Philipp |
  9. Ernemann, Ulrike |
  10. Klose, Uwe |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-09-27
1000 Erschienen in
1000 Quellenangabe
  • 64(3):553-563
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00234-021-02814-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850258/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Patients with Moyamoya Angiopathy (MMA) require hemodynamic evaluation to assess the risk of stroke. Assessment of cerebral blood flow with [!##!Methods!#!Patients with MMA underwent rs-fMRI and bh-fMRI in the same MRI session. Maps of the CVR gained by both modalities were compared retrospectively by calculating the correlation between the mean CVR of 12 volumes of interest. Additionally, the rs-maps of a subgroup of patients were compared to CPR-maps gained by [!##!Results!#!The comparison of the rs-maps and the bh-maps of 24 patients revealed a good correlation (Pearson's r = 0.71 ± 0.13; preoperative patients: Pearson's r = 0.71 ± 0.17; postoperative patients: Pearson's r = 0.71 ± 0.11). The comparison of 7 rs-fMRI data sets to the corresponding [!##!Conclusion!#!The present analysis indicates that rs-fMRI might be a promising non-invasive method with almost no patient cooperation needed to evaluate the CVR. Further prospective studies are required.
1000 Sacherschließung
lokal Cerebrovascular reactivity
lokal Water [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Functional Neuroradiology
lokal Moyamoya Disease/diagnostic imaging [MeSH]
lokal Moyamoya Angiopathy
lokal Cerebrovascular Circulation/physiology [MeSH]
lokal Resting-state fMRI
lokal Brain/blood supply [MeSH]
lokal Hemodynamics [MeSH]
lokal Magnetic Resonance Imaging/methods [MeSH]
lokal Breath-hold fMRI
lokal [
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-4105-5131|https://orcid.org/0000-0003-4487-2807|https://orcid.org/0000-0001-7604-3419|https://orcid.org/0000-0001-6703-6030|https://orcid.org/0000-0002-2399-3020|https://orcid.org/0000-0002-1627-9937|https://orcid.org/0000-0001-5179-5243|https://orcid.org/0000-0001-8336-750X|https://orcid.org/0000-0003-1330-1235|https://orcid.org/0000-0001-5236-3450
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