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1000 Titel
  • Reversible severe glycogenic hepatopathy in type 1 diabetes
1000 Autor/in
  1. de Laffolie, Jan |
  2. Kamrath, Clemens |
  3. Burchert, Diana |
  4. Böttcher, Claudia |
  5. Wudy, Stefan Alexander |
  6. Zimmer, Klaus-Peter |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-01-20
1000 Erschienen in
1000 Quellenangabe
  • 172(5-6):144-147
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s10354-020-00795-6 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975768/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Case presentation!#!We report a case of severe glycogenic hepatopathy in a 17-year-old boy with poorly controlled type 1 diabetes. On presentation, major findings included unexplained pronounced hepatomegaly and increased liver enzymes, ferritin, and triglycerides. Histology and electron microscopy evaluation showed severe glycogen storage, steatosis, and signs of fibrosis, resembling the histomorphological findings of Mauriac syndrome. After information about the nature of the disease and intensification of insulin therapy with insulin pump, liver enzymes, ferritin, and triglycerides normalized within 1 month.!##!Conclusion!#!Glycogenic hepatopathy is a rare but important potential complication in poorly controlled juvenile diabetic patients. With improved metabolic control, it is fully reversible.
1000 Sacherschließung
lokal Adolescent [MeSH]
lokal Diabetes Mellitus, Type 1/drug therapy [MeSH]
lokal Hepatomegaly/pathology [MeSH]
lokal Hepatomegaly/complications [MeSH]
lokal Humans [MeSH]
lokal Glycogen
lokal Metabolic control
lokal Glycogen/metabolism [MeSH]
lokal Liver Diseases/pathology [MeSH]
lokal Diabetes
lokal Male [MeSH]
lokal Liver Diseases/complications [MeSH]
lokal Diabetes Mellitus, Type 1/complications [MeSH]
lokal Hepatopathy
lokal Diabetes Mellitus, Type 1/diagnosis [MeSH]
lokal Liver Diseases/diagnosis [MeSH]
lokal Pediatric hepatology
lokal Case Report
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-1023-7442|https://frl.publisso.de/adhoc/uri/S2FtcmF0aCwgQ2xlbWVucw==|https://frl.publisso.de/adhoc/uri/QnVyY2hlcnQsIERpYW5h|https://frl.publisso.de/adhoc/uri/QsO2dHRjaGVyLCBDbGF1ZGlh|https://frl.publisso.de/adhoc/uri/V3VkeSwgU3RlZmFuIEFsZXhhbmRlcg==|https://frl.publisso.de/adhoc/uri/WmltbWVyLCBLbGF1cy1QZXRlcg==
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  • DeepGreen-ID: 3e1ef5ffc46a4aa1bfdd59c5b6bdcd51 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Dateien
  1. Reversible severe glycogenic hepatopathy in type 1 diabetes
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1000 Erstellt am 2023-05-04T10:23:04.427+0200
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1000 Zuletzt bearbeitet Fri Oct 20 23:34:14 CEST 2023
1000 Objekt bearb. Fri Oct 20 23:34:14 CEST 2023
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