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1000 Titel
  • Relevance of comorbidities and antithrombotic medication as risk factors for reoperation in patients with chronic subdural hematoma
1000 Autor/in
  1. Younsi, Alexander |
  2. Riemann, Lennart |
  3. Habel, Cleo |
  4. Fischer, Jessica |
  5. Beynon, Christopher |
  6. Unterberg, Andreas W. |
  7. Zweckberger, Klaus |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-09
1000 Erschienen in
1000 Quellenangabe
  • 45(1):729-739
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s10143-021-01537-x |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827308/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • In an aging Western society, the incidence of chronic subdural hematomas (cSDH) is continuously increasing. In this study, we reviewed our clinical management of cSDH patients and identified predictive factors for the need of reoperation due to residual or recurrent hematomas with a focus on the use of antithrombotic drugs. In total, 623 patients who were treated for cSDH with surgical evacuation between 2006 and 2016 at our department were retrospectively analyzed. Clinical and radiological characteristics and laboratory parameters were investigated as possible predictors of reoperation with univariate and multivariate analyses. Additionally, clinical outcome measures were compared between patients on anticoagulants, on antiplatelets, and without antithrombotic medication. In univariate analyses, patients on anticoagulants and antiplatelets presented significantly more often with comorbidities, were significantly older, and their risk for perioperative complications was significantly increased. Nevertheless, their clinical outcome was comparable to that of patients without antithrombotics. In multivariate analysis, only the presence of comorbidities, but not antithrombotics, was an independent predictor for the need for reoperations. Patients on antithrombotics do not seem to necessarily have a significantly increased risk for residual hematomas or rebleeding requiring reoperation after cSDH evacuation. More precisely, the presence of predisposing comorbidities might be a key independent risk factor for reoperation. Importantly, the clinical outcomes after surgical evacuation of cSDH are comparable between patients on anticoagulants, antiplatelets, and without antithrombotics.
1000 Sacherschließung
lokal Comorbidities
lokal Reoperation
lokal Hematoma, Subdural, Chronic/epidemiology [MeSH]
lokal Humans [MeSH]
lokal Drainage [MeSH]
lokal Retrospective Studies [MeSH]
lokal Risk Factors [MeSH]
lokal Antiplatelets
lokal Reoperation [MeSH]
lokal Risk factors
lokal Fibrinolytic Agents/adverse effects [MeSH]
lokal Original Article
lokal Hematoma, Subdural, Chronic/surgery [MeSH]
lokal Chronic subdural hematoma
lokal Anticoagulants
lokal Antithrombotics
lokal Hematoma, Subdural, Chronic/drug therapy [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-8218-9243|https://frl.publisso.de/adhoc/uri/UmllbWFubiwgTGVubmFydA==|https://frl.publisso.de/adhoc/uri/SGFiZWwsIENsZW8=|https://frl.publisso.de/adhoc/uri/RmlzY2hlciwgSmVzc2ljYQ==|https://frl.publisso.de/adhoc/uri/QmV5bm9uLCBDaHJpc3RvcGhlcg==|https://frl.publisso.de/adhoc/uri/VW50ZXJiZXJnLCBBbmRyZWFzIFcu|https://frl.publisso.de/adhoc/uri/WndlY2tiZXJnZXIsIEtsYXVz
1000 Hinweis
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1000 Erstellt am 2023-05-04T10:40:45.299+0200
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1000 Zuletzt bearbeitet 2023-10-20T23:52:32.236+0200
1000 Objekt bearb. Fri Oct 20 23:52:32 CEST 2023
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