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1000 Titel
  • Versatility and clinical effectiveness of a synthetic sealing hemostatic patch as alternative to parenchyma suturing in laparoscopic partial nephrectomy
1000 Autor/in
  1. Erne, Eva |
  2. Kruck, Stephan |
  3. Todenhoefer, Tilman |
  4. Aufderklamm, Stefan |
  5. Amend, Bastian |
  6. Bedke, Jens |
  7. Stenzl, Arnulf |
  8. Rausch, Steffen |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-02-16
1000 Erschienen in
1000 Quellenangabe
  • 36(1):663-669
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00464-021-08333-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741715/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Improvements in laparoscopic partial nephrectomy (LPN) in order to minimize perioperative warm ischemia time (WIT), complications, and consequently patient outcome are desirable. Veriset™ is a ready-to-use hemostatic patch of absorbable oxidized cellulose and hydrogel components that has earlier been implemented in vascular and hepatic surgery. We report our experience using this device in LPN.!##!Methods!#!Patients with a solitary malignant renal mass suspicious for renal cancer underwent LPN with either the use of Veriset™ hemostatic patch (n = 40) or conventional suture technique (n = 40). Patient characteristics, operation time and WIT, postoperative course and complications were recorded retrospectively. Tumor complexity was calculated according to the R.E.N.A.L. score. Outcome was determined according to the 'trifecta' criteria (negative surgical margin, WIT < 25 min, no complications within 30 days).!##!Results!#!No significant differences with regard to clinical parameters and median R.E.N.A.L. score (6) were observed between both groups. Operation time (mean 127.1 min vs. 162. 8 min; p = 0.001) and WIT were both lower in the Veriset™ group (14.6 min vs. 20.6 min; p = 0.01). No differences in surgical margins (p = 0.602) and overall complication rates at 30 (p = 0.599) and 90 days (p = 0.611) postoperatively were noticed. The surgical outcome according to 'trifecta' was achieved in 65% of patients using Veriset™ and in 57.5% of patients by suture closure, respectively.!##!Conclusion!#!The hemostatic Veriset™ patch can successfully be implemented in LPN. Handling and application appear favorable, thereby reducing operation time and WIT. The present results suggest that the device may represent an alternative to parenchyma suturing in LPN.
1000 Sacherschließung
lokal Laparoscopy/methods [MeSH]
lokal Veriset
lokal Laparoscopic partial nephrectomy
lokal Hemostatics/therapeutic use [MeSH]
lokal Humans [MeSH]
lokal Sutures [MeSH]
lokal Treatment Outcome [MeSH]
lokal Kidney Neoplasms/surgery [MeSH]
lokal Retrospective Studies [MeSH]
lokal Kidney Neoplasms/pathology [MeSH]
lokal Hemopatch
lokal Complication
lokal Article
lokal Nephrectomy/methods [MeSH]
lokal Hemostasis
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RXJuZSwgRXZh|https://frl.publisso.de/adhoc/uri/S3J1Y2ssIFN0ZXBoYW4=|https://frl.publisso.de/adhoc/uri/VG9kZW5ob2VmZXIsIFRpbG1hbg==|https://frl.publisso.de/adhoc/uri/QXVmZGVya2xhbW0sIFN0ZWZhbg==|https://frl.publisso.de/adhoc/uri/QW1lbmQsIEJhc3RpYW4=|https://frl.publisso.de/adhoc/uri/QmVka2UsIEplbnM=|https://frl.publisso.de/adhoc/uri/U3RlbnpsLCBBcm51bGY=|https://orcid.org/0000-0002-6398-8701
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1000 Erstellt am 2023-05-09T10:11:04.832+0200
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1000 Zuletzt bearbeitet 2023-10-21T01:47:38.473+0200
1000 Objekt bearb. Sat Oct 21 01:47:38 CEST 2023
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