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1000 Titel
  • Surgical treatment of liver metastases from non-colorectal non-neuroendocrine carcinomas
1000 Autor/in
  1. Bauschke, Astrid |
  2. Altendorf-Hofmann, Annelore |
  3. Homman, Merten |
  4. Manger, Thomas |
  5. Pertschy, Jörg |
  6. Helfritzsch, Herry |
  7. Göbel, Hubert |
  8. Settmacher, Utz |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-04-20
1000 Erschienen in
1000 Quellenangabe
  • 148(2):503-515
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00432-021-03631-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800927/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Introduction!#!In the literature, results after surgical treatment of non-colorectal non-neuroendocrine liver metastases (NCNNLM) are reported that are often inferior to those from colorectal liver metastases. The selection of patients with favorable tumor biology is currently still a matter of discussion.!##!Materials/methods!#!The retrospective data analysis was based on data that were collected for the multicenter study 'Role of surgical treatment for non-colorectal liver metastases' in county Thuringia.!##!Results!#!For the study, 637 patients were included from 1995 to 2018. 5 and 10-year survival of R0 resected patients were 33% and 19%, respectively. In the multi-variate analysis of the entire group, sex, timing, disease-free interval, number of metastases, R-classification as well as lymph node status of the primary lesion showed an independent statistical influence on the 5-year survival. In the group of R0 resected patients, disease-free interval, number of metastases and lymph node status of the primary lesion influenced the 5-year survival in the multi-variate analysis. In kidney malignancies, R-classification, timing and number of liver metastases were statistically significant in the multi-variate analysis of the 5-year survival, in mamma carcinomas only the R-classification.!##!Conclusion!#!The Adam score identifies some risk factors which influence prognosis in most but not in all tumor entities. For kidney cancer and breast cancer it can be simplified.
1000 Sacherschließung
lokal Hepatectomy/trends [MeSH]
lokal Liver Neoplasms/surgery [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Liver Neoplasms/mortality [MeSH]
lokal Aged [MeSH]
lokal Original Article – Clinical Oncology
lokal Non-colorectal non-neuroendocrine liver metastases
lokal Germany/epidemiology [MeSH]
lokal Survival
lokal Male [MeSH]
lokal Hepatectomy/mortality [MeSH]
lokal Surgery
lokal Female [MeSH]
lokal History, 21st Century [MeSH]
lokal Liver Neoplasms/diagnosis [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Survival Analysis [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Hepatectomy/methods [MeSH]
lokal Liver Neoplasms/secondary [MeSH]
lokal Prognosis [MeSH]
lokal History, 20th Century [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-9941-5323|https://frl.publisso.de/adhoc/uri/QWx0ZW5kb3JmLUhvZm1hbm4sIEFubmVsb3Jl|https://frl.publisso.de/adhoc/uri/SG9tbWFuLCBNZXJ0ZW4=|https://frl.publisso.de/adhoc/uri/TWFuZ2VyLCBUaG9tYXM=|https://frl.publisso.de/adhoc/uri/UGVydHNjaHksIErDtnJn|https://frl.publisso.de/adhoc/uri/SGVsZnJpdHpzY2gsIEhlcnJ5|https://frl.publisso.de/adhoc/uri/R8O2YmVsLCBIdWJlcnQ=|https://frl.publisso.de/adhoc/uri/U2V0dG1hY2hlciwgVXR6
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1000 Erstellt am 2023-05-09T10:27:23.225+0200
1000 Erstellt von 322
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1000 Zuletzt bearbeitet 2023-10-21T02:10:27.197+0200
1000 Objekt bearb. Sat Oct 21 02:10:27 CEST 2023
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