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1000 Titel
  • Impact of early intensified postoperative corticosteroids on immune reaction rates after Descemet membrane endothelial keratoplasty (DMEK)
1000 Autor/in
  1. Schaub, Friederike |
  2. Mestanoglu, Mert |
  3. Cursiefen, Claus |
  4. Hos, Deniz |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-09-01
1000 Erschienen in
1000 Quellenangabe
  • 260(2):693-695
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00417-021-05393-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8786744/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!To investigate short-term (3 months follow-up) changes in visual quality following Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy (FED).!##!Methods!#!In this prospective institutional case series, 51 patients that underwent DMEK for FED were included. Assessment included the Quality of Vision (QoV) questionnaire preoperatively, at 1 month, and 3 months after surgery. Secondary outcome measures were anterior segment parameters acquired by Scheimpflug imaging, corrected distance visual acuity (CDVA), and endothelial cell density (ECD).!##!Results!#!Glare, hazy vision, blurred vision, and daily fluctuation in vision were the symptoms mostly reported preoperatively. All symptoms demonstrated a significant reduction of item scores for severity, frequency, and bothersome in the course after DMEK (P < 0.01). Glare and fluctuation in vision remained to some extent during the follow-up period (median score = 1). Preoperatively, corneal densitometry correlated moderately to weakly with severity of hazy vision (r!##!Conclusions!#!Following DMEK for FED, patient-reported visual symptoms assessed by the QoV questionnaire represent a useful tool providing valuable information on the impact of DMEK on visual quality that cannot be directly estimated by morphological parameters and visual acuity only.
1000 Sacherschließung
lokal Ophthalmology
lokal Adrenal Cortex Hormones [MeSH]
lokal Endothelium, Corneal [MeSH]
lokal Fuchs' Endothelial Dystrophy/surgery [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Descemet Stripping Endothelial Keratoplasty [MeSH]
lokal Descemet Membrane/surgery [MeSH]
lokal Letter to the Editor
lokal Cell Count [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-2648-1626|https://frl.publisso.de/adhoc/uri/TWVzdGFub2dsdSwgTWVydA==|https://frl.publisso.de/adhoc/uri/Q3Vyc2llZmVuLCBDbGF1cw==|https://frl.publisso.de/adhoc/uri/SG9zLCBEZW5peg==
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1000 Erstellt am 2023-05-09T11:17:31.494+0200
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