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1000 Titel
  • Lethal form of a late-onset aquaporin-4 antibody-positive NMOSD related to the immune checkpoint inhibitor nivolumab
1000 Autor/in
  1. Weiss, David |
  2. Cantré, Daniel |
  3. Zettl, Uwe K. |
  4. Storch, Alexander |
  5. Prudlo, Johannes |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-28
1000 Erschienen in
1000 Quellenangabe
  • 269(5):2778-2780
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00415-021-10913-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021101/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!To investigate the learning curve of vitreoretinal (VR) surgeons beginning training in retinal detachment (RD) surgery.!##!Methods!#!The files of all consecutive patients undergoing VR surgery for uncomplicated RD between Jan 2005 und Mar 2020 were retrospectively reviewed. Successful outcome was defined as no retinal redetachment within 3 months after surgery.!##!Results!#!Ten surgeons started their VR career during this period. Together, these 10 surgeons performed 3786 RD operations (mean 379; median 251; range 71-1053). Primary success rate after one operation was 90% (3420 of 3786). When starting to operate retinal detachments, VR surgeons had a primary success rate of about 80%. Redetachment rates steadily decreased and stabilized at just under 10% after about 200 operations. Beginners needed more than twice the time for the procedure compared to experienced surgeons. The individual learning curves varied widely. In our series, female surgeons seem to have a faster learning curve.!##!Conclusion!#!RD surgery performed by VR surgeons in training had acceptable results. With increasing experience, success rates continuously improve reaching stable levels after approximately 200 operations. The training of VR surgeons requires considerable resources.
1000 Sacherschließung
lokal Neurology
lokal Neuromyelitis Optica/drug therapy [MeSH]
lokal Aquaporin 4 [MeSH]
lokal Immune Checkpoint Inhibitors/adverse effects [MeSH]
lokal Humans [MeSH]
lokal Letter to the Editors
lokal Autoantibodies [MeSH]
lokal Neuromyelitis Optica/diagnostic imaging [MeSH]
lokal Neuroradiology
lokal Neurosciences
lokal Nivolumab/adverse effects [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-1333-6289|https://frl.publisso.de/adhoc/uri/Q2FudHLDqSwgRGFuaWVs|https://frl.publisso.de/adhoc/uri/WmV0dGwsIFV3ZSBLLg==|https://frl.publisso.de/adhoc/uri/U3RvcmNoLCBBbGV4YW5kZXI=|https://frl.publisso.de/adhoc/uri/UHJ1ZGxvLCBKb2hhbm5lcw==
1000 Hinweis
  • DeepGreen-ID: 166596d2b0d7415dba07fed736c0108d ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 @id frl:6450198.rdf
1000 Erstellt am 2023-05-09T11:32:52.395+0200
1000 Erstellt von 322
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1000 Zuletzt bearbeitet 2023-10-14T08:34:05.981+0200
1000 Objekt bearb. Sat Oct 14 08:34:05 CEST 2023
1000 Vgl. frl:6450198
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  1. oai:frl.publisso.de:frl:6450198 |
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