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1000 Titel
  • The log odds of positive neck lymph nodes is a superior lymph node predictor for overall survival in head and neck cancer: a population-based analysis in Germany
1000 Autor/in
  1. Kouka, Mussab |
  2. Al-Ahmar, Elisa |
  3. Büntzel, Jens |
  4. Kaftan, Holger |
  5. Böger, Daniel |
  6. Müller, Andreas |
  7. Schultze-Mosgau, Stefan |
  8. Ernst, Thomas |
  9. Guntinas-Lichius, Orlando |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-22
1000 Erschienen in
1000 Quellenangabe
  • 279(7):3587-3595
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00405-021-07176-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9130179/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!This population-based study investigated the influence of different lymph node (LN) classifications on overall survival (OS) in head and neck cancer (HNC).!##!Methods!#!401 patients (median age: 57 years; 47% stage IV) of the Thuringian cancer registries with diagnosis of a primary HNC receiving a neck dissection (ND) in 2009 and 2010 were included. OS was assessed in relation to total number of LN removed, number of positive LN, LN ratio, and log odds of positive LN (LODDS).!##!Results!#!Mean number of LODDS was 0-0.96 ± 0.57. When limiting the multivariate analysis to TNM stage, only the UICC staging (stage IV: HR 9.218; 95% CI 2.721-31.224; p < 0.001) and LODDS >  - 1.0 (HR 2.120; 95% CI 1.129-3.982; p = 0.019) were independently associated with lower OS.!##!Conclusion!#!LODDS was an independent and superior predictor for OS in HNC in a population-based setting with representative real-life data.
1000 Sacherschließung
lokal Lymph Nodes/pathology [MeSH]
lokal Cervical lymph node metastases
lokal Humans [MeSH]
lokal Middle Aged [MeSH]
lokal Tumor staging
lokal Germany/epidemiology [MeSH]
lokal Head and Neck Neoplasms/surgery [MeSH]
lokal Neoplasm Staging [MeSH]
lokal Lymph node classifications
lokal Survival
lokal Head and neck cancer
lokal Lymphatic Metastasis/pathology [MeSH]
lokal Prognosis [MeSH]
lokal Head and Neck
lokal Cancer registry
lokal Head and Neck Neoplasms/pathology [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S291a2EsIE11c3NhYg==|https://frl.publisso.de/adhoc/uri/QWwtQWhtYXIsIEVsaXNh|https://frl.publisso.de/adhoc/uri/QsO8bnR6ZWwsIEplbnM=|https://frl.publisso.de/adhoc/uri/S2FmdGFuLCBIb2xnZXI=|https://frl.publisso.de/adhoc/uri/QsO2Z2VyLCBEYW5pZWw=|https://frl.publisso.de/adhoc/uri/TcO8bGxlciwgQW5kcmVhcw==|https://frl.publisso.de/adhoc/uri/U2NodWx0emUtTW9zZ2F1LCBTdGVmYW4=|https://frl.publisso.de/adhoc/uri/RXJuc3QsIFRob21hcw==|https://orcid.org/0000-0001-9671-0784
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1000 Erstellt am 2023-05-09T12:08:36.191+0200
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