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1000 Titel
  • ECOG and BMI as preoperative risk factors for severe postoperative complications in ovarian cancer patients: results of a prospective study (RISC-GYN—trial)
1000 Autor/in
  1. Inci, Guelhan |
  2. Rasch, Julia |
  3. Woopen, Hannah |
  4. Mueller, Kristina |
  5. Richter, Rolf |
  6. Sehouli, Jalid |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-24
1000 Erschienen in
1000 Quellenangabe
  • 304(5):1323-1333
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00404-021-06116-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8490255/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Accompanying co-morbidities in patients with ovarian cancer are of major relevance for scheduling debulking surgery, especially in the anesthesiological consultations. Aim of this study was to evaluate the impact of co-morbidities and patient characteristics on postoperative complications.!##!Methods!#!Patients undergoing maximal cytoreductive surgery were prospectively enrolled from October 2015 to January 2017. Various variables were recorded, such as the Charlson comorbidity index, Eastern cooperative oncology group scale of performance status (ECOG PS) and the American society of anesthesiologists physical status classification system (ASA PS). Surgical complications were graded using the Clavien-Dindo criteria. Logistic regression models were used to analyze risk factors for severe postoperative complications.!##!Results!#!Of 106 enrolled patients, 19 (17.9%) developed severe postoperative complications grade ≥ IIIb according to Clavien-Dindo criteria. In the multivariable regression analysis impaired (ECOG PS) > 1 (odds ratio OR) 13.34, 95% confidence interval (CI) 1.74-102.30, p = 0.01), body mass index (BMI) > 25 kg/m!##!Conclusion!#!We demonstrated that neither the presence of a certain comorbidity nor the summation of the co-morbidities were associated with adverse outcome. Patient characteristics, such as ECOG PS > 1 and obesity (BMI > 25 kg/m
1000 Sacherschließung
lokal Female [MeSH]
lokal Postoperative complications
lokal Ovarian cancer
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal Body mass index
lokal Ovarian Neoplasms/surgery [MeSH]
lokal Postoperative Complications/epidemiology [MeSH]
lokal Retrospective Studies [MeSH]
lokal Risk Factors [MeSH]
lokal Body Mass Index [MeSH]
lokal Postoperative Complications/etiology [MeSH]
lokal Comorbidity
lokal Gynecology
lokal Surgery
lokal Gynecologic Oncology
lokal Performance status
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-3871-7440|https://frl.publisso.de/adhoc/uri/UmFzY2gsIEp1bGlh|https://frl.publisso.de/adhoc/uri/V29vcGVuLCBIYW5uYWg=|https://frl.publisso.de/adhoc/uri/TXVlbGxlciwgS3Jpc3RpbmE=|https://frl.publisso.de/adhoc/uri/UmljaHRlciwgUm9sZg==|https://frl.publisso.de/adhoc/uri/U2Vob3VsaSwgSmFsaWQ=
1000 Hinweis
  • DeepGreen-ID: 1c0c013fabcc45d782bb21121d2c46a6 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-05-09T12:48:06.934+0200
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1000 Zuletzt bearbeitet 2023-10-21T03:46:21.932+0200
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