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1000 Titel
  • Prescription of analgesics in patients with rheumatic diseases in Germany
1000 Titelzusatz
  • Verordnung von Schmerzmitteln bei Patienten mit rheumatischen Erkrankungen in Deutschland
1000 Autor/in
  1. Albrecht, K. |
  2. Marschall, U. |
  3. Callhoff, J. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-04-07
1000 Erschienen in
1000 Quellenangabe
  • 80(Suppl 2):68-75
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00393-021-00971-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752520/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Objective!#!To investigate the prescription frequency of analgesics in persons diagnosed with rheumatoid arthritis (RA), axial spondylarthritis (axSpA), psoriatic arthritis (PsA) and systemic lupus erythematosus (SLE) in 2019 using claims data.!##!Methods!#!Persons ≥ 18 years insured in 2019 with a diagnosis of RA (M05, M06), axSpA (M45), PsA (M07.0-3) or SLE (M32.1,8,9) were included. Analgesics were identified by the anatomic therapeutic classification (ATC) system. Reported is the percentage of individuals with ≥ 1 analgesics prescription for the respective rheumatic diagnosis in 2019 and for opioids age-standardized in each of the years 2005-2019. In addition, the proportion of long-term opioid use (prescriptions in ≥ 3 consecutive quarter years) in 2006 and 2019 is compared.!##!Results!#!Metamizole (29-33%) was the most commonly prescribed analgesic. Nonsteroidal anti-inflammatory drugs (NSAID)/coxibs were prescribed from 35% (SLE) to 50% (axSpA). Of the patients 11-13% were prescribed weak and 6-8% strong opioids. From 2005 to 2019, the proportion of persons with an opioid prescription remained stable, with similar or slightly decreasing proportions of weak opioids and more frequent prescriptions of strong opioids. The proportion of long-term opioid prescriptions increased from 2006 to 2019 from 8.9% to 11.0% (RA), from 6.9% to 9.1% (axSPA), from 7.8% to 9.5% (PsA), and from 7.5% to 8.8% (SLE), corresponding to a 17-24% increase.!##!Conclusion!#!The prescription of opioids for persons with inflammatory rheumatic diagnoses is not as high in Germany as in other countries; however, the proportion of long-term prescriptions has considerably increased. The frequent prescription of metamizole is conspicuous.
1000 Sacherschließung
lokal Rheumatic Diseases/drug therapy [MeSH]
lokal Rheumatic Diseases/diagnosis [MeSH]
lokal Drug Prescriptions [MeSH]
lokal Humans [MeSH]
lokal Prescription frequency
lokal Analgesics/therapeutic use [MeSH]
lokal Opioids
lokal Analgesics
lokal Practice Patterns, Physicians' [MeSH]
lokal Germany/epidemiology [MeSH]
lokal Health care
lokal Data Analysis [MeSH]
lokal Opioide
lokal Rheumatic Diseases/epidemiology [MeSH]
lokal Analgesics, Opioid/therapeutic use [MeSH]
lokal Verordnungshäufigkeit
lokal Originalien
lokal Inflammatory rheumatic diseases
lokal Analgetika
lokal Entzündlich rheumatische Erkrankungen
lokal Versorgung
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QWxicmVjaHQsIEsu|https://frl.publisso.de/adhoc/uri/TWFyc2NoYWxsLCBVLg==|https://frl.publisso.de/adhoc/uri/Q2FsbGhvZmYsIEou
1000 Hinweis
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1000 Erstellt am 2023-05-11T11:12:30.727+0200
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1000 beschreibt frl:6450834
1000 Zuletzt bearbeitet Fri Oct 20 10:26:46 CEST 2023
1000 Objekt bearb. Fri Oct 20 10:26:46 CEST 2023
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