Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience

  1. Westermann, Dirk
  2. Ludwig, Sebastian ORCID logo
  3. Kalbacher, Daniel
  4. Spink, Clemens
  5. Linder, Matthias
  6. Bhadra, Oliver D.
  7. Nikorowitsch, Julius
  8. Waldschmidt, Lara
  9. Demal, Till
  10. Voigtländer, Lisa
  11. Schaefer, Andreas
  12. Seiffert, Moritz
  13. Pecha, Simon
  14. Schofer, Niklas
  15. Greenbaum, Adam B.
  16. Reichenspurner, Hermann
  17. Blankenberg, Stefan
  18. Conradi, Lenard
  19. Schirmer, Johannes

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1000 Titel
  • Prevention of coronary obstruction in patients at risk undergoing transcatheter aortic valve implantation: the Hamburg BASILICA experience
1000 Autor/in
  1. Westermann, Dirk |
  2. Ludwig, Sebastian |
  3. Kalbacher, Daniel |
  4. Spink, Clemens |
  5. Linder, Matthias |
  6. Bhadra, Oliver D. |
  7. Nikorowitsch, Julius |
  8. Waldschmidt, Lara |
  9. Demal, Till |
  10. Voigtländer, Lisa |
  11. Schaefer, Andreas |
  12. Seiffert, Moritz |
  13. Pecha, Simon |
  14. Schofer, Niklas |
  15. Greenbaum, Adam B. |
  16. Reichenspurner, Hermann |
  17. Blankenberg, Stefan |
  18. Conradi, Lenard |
  19. Schirmer, Johannes |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-22
1000 Erschienen in
1000 Quellenangabe
  • 110(12):1900-1911
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00392-021-01881-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639537/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Objectives!#!This study aimed to assess the clinical outcome of the bioprosthetic or native aortic scallop intentional laceration to prevent iatrogenic coronary obstruction (BASILICA) technique in a single-center patient cohort considered at high or prohibitive risk of transcatheter aortic valve implantation (TAVI)-induced coronary obstruction.!##!Methods!#!Between October 2019 and January 2021, a total of 15 consecutive patients (age 81.0 [78.1, 84.4] years; 53.3% female; EuroSCORE II 10.6 [6.3, 14.8] %) underwent BASILICA procedure prior to TAVI at our institution. Indications for TAVI were degeneration of stented (n = 12, 80.0%) or stentless (n = 1, 6.7%) bioprosthetic aortic valves, or calcific stenosis of native aortic valves (n = 2, 13.3%), respectively. Individual risk of TAVI-induced coronary obstruction was assessed by pre-procedural computed tomography analysis. Procedural and 30-day outcomes were documented in accordance with Valve Academic Research Consortium (VARC)-2 criteria.!##!Results!#!BASILICA was attempted for single left coronary cusp in 12 patients (80.0%), for single right coronary cusp in 2 patients (13.3%), and for both cusps in 1 patient (6.7%), respectively. The procedure was feasible in 13 patients (86.7%) resulting in effective prevention of coronary obstruction, whilst TAVI was performed without prior successful bioprosthetic leaflet laceration in two patients (13.3%). In one of these patients (6.7%), additional chimney stenting immediately after TAVI was performed. No all-cause deaths or strokes were documented after 30 days.!##!Conclusion!#!The BASILICA technique appears to be a feasible, safe and effective concept to avoid iatrogenic coronary artery obstruction during TAVI in both native and bioprosthetic valves of patients at high or prohibitive risk. ClinicalTrials.gov Identifier: NCT04227002 (Hamburg AoRtic Valve cOhoRt).
1000 Sacherschließung
lokal Coronary Vessels/diagnostic imaging [MeSH]
lokal Fluoroscopy [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Aortic Valve/surgery [MeSH]
lokal Postoperative Complications/diagnosis [MeSH]
lokal Coronary obstruction
lokal Tomography, X-Ray Computed [MeSH]
lokal Coronary Occlusion/prevention
lokal Male [MeSH]
lokal Postoperative Complications/prevention
lokal Echocardiography [MeSH]
lokal Heart Valve Prosthesis/adverse effects [MeSH]
lokal Aortic Valve Stenosis/surgery [MeSH]
lokal Prosthesis Design [MeSH]
lokal Female [MeSH]
lokal Iatrogenic Disease/prevention
lokal Follow-Up Studies [MeSH]
lokal Aortic Valve/diagnostic imaging [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Transcatheter Aortic Valve Replacement/adverse effects [MeSH]
lokal Coronary Angiography [MeSH]
lokal Original Paper
lokal Coronary Occlusion/diagnosis [MeSH]
lokal Transcatheter aortic valve implantation
lokal Bioprosthesis/adverse effects [MeSH]
lokal BASILICA
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/V2VzdGVybWFubiwgRGlyaw==|https://orcid.org/0000-0002-5752-4951|https://frl.publisso.de/adhoc/uri/S2FsYmFjaGVyLCBEYW5pZWw=|https://frl.publisso.de/adhoc/uri/U3BpbmssIENsZW1lbnM=|https://frl.publisso.de/adhoc/uri/TGluZGVyLCBNYXR0aGlhcw==|https://frl.publisso.de/adhoc/uri/QmhhZHJhLCBPbGl2ZXIgRC4=|https://frl.publisso.de/adhoc/uri/Tmlrb3Jvd2l0c2NoLCBKdWxpdXM=|https://frl.publisso.de/adhoc/uri/V2FsZHNjaG1pZHQsIExhcmE=|https://frl.publisso.de/adhoc/uri/RGVtYWwsIFRpbGw=|https://frl.publisso.de/adhoc/uri/Vm9pZ3Rsw6RuZGVyLCBMaXNh|https://frl.publisso.de/adhoc/uri/U2NoYWVmZXIsIEFuZHJlYXM=|https://frl.publisso.de/adhoc/uri/U2VpZmZlcnQsIE1vcml0eg==|https://frl.publisso.de/adhoc/uri/UGVjaGEsIFNpbW9u|https://frl.publisso.de/adhoc/uri/U2Nob2ZlciwgTmlrbGFz|https://frl.publisso.de/adhoc/uri/R3JlZW5iYXVtLCBBZGFtIEIu|https://frl.publisso.de/adhoc/uri/UmVpY2hlbnNwdXJuZXIsIEhlcm1hbm4=|https://frl.publisso.de/adhoc/uri/QmxhbmtlbmJlcmcsIFN0ZWZhbg==|https://frl.publisso.de/adhoc/uri/Q29ucmFkaSwgTGVuYXJk|https://frl.publisso.de/adhoc/uri/U2NoaXJtZXIsIEpvaGFubmVz
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1000 Erstellt am 2023-05-11T11:30:20.937+0200
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1000 Zuletzt bearbeitet 2023-10-20T10:27:11.862+0200
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