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1000 Titel
  • Diagnostic accuracy of color-coded virtual noncalcium reconstructions derived from portal venous phase dual-energy CT in the assessment of lumbar disk herniation
1000 Autor/in
  1. Koch, Vitali |
  2. Albrecht, Moritz H. |
  3. Gruenewald, Leon D. |
  4. Yel, Ibrahim |
  5. Eichler, Katrin |
  6. Gruber-Rouh, Tatjana |
  7. Hammerstingl, Renate M. |
  8. Burck, Iris |
  9. Wichmann, Julian L. |
  10. Alizadeh, Leona S. |
  11. Vogl, Thomas J. |
  12. Lenga, Lukas |
  13. Mader, Christoph |
  14. Martin, Simon S. |
  15. Mazziotti, Silvio |
  16. D’Angelo, Tommaso |
  17. Booz, Christian |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-24
1000 Erschienen in
1000 Quellenangabe
  • 32(4):2168-2177
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00330-021-08354-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921028/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Objectives!#!To investigate the diagnostic accuracy of color-coded contrast-enhanced dual-energy CT virtual noncalcium (VNCa) reconstructions for the assessment of lumbar disk herniation compared to unenhanced VNCa imaging.!##!Methods!#!A total of 91 patients were retrospectively evaluated (65 years ± 16; 43 women) who had undergone third-generation dual-source dual-energy CT and 3.0-T MRI within an examination interval up to 3 weeks between November 2019 and December 2020. Eight weeks after assessing unenhanced color-coded VNCa reconstructions for the presence and degree of lumbar disk herniation, corresponding contrast-enhanced portal venous phase color-coded VNCa reconstructions were independently analyzed by the same five radiologists. MRI series were additionally analyzed by one highly experienced musculoskeletal radiologist and served as reference standard.!##!Results!#!MRI depicted 210 herniated lumbar disks in 91 patients. VNCa reconstructions derived from contrast-enhanced CT scans showed similar high overall sensitivity (93% vs 95%), specificity (94% vs 95%), and accuracy (94% vs 95%) for the assessment of lumbar disk herniation compared to unenhanced VNCa images (all p > .05). Interrater agreement in VNCa imaging was excellent for both, unenhanced and contrast-enhanced CT (κ = 0.84 vs κ = 0.86; p > .05). Moreover, ratings for diagnostic confidence, image quality, and noise differed not significantly between unenhanced and contrast-enhanced VNCa series (all p > .05).!##!Conclusions!#!Color-coded VNCa reconstructions derived from contrast-enhanced dual-energy CT yield similar diagnostic accuracy for the depiction of lumbar disk herniation compared to unenhanced VNCa imaging and therefore may improve opportunistic retrospective lumbar disk herniation assessment, particularly in case of staging CT examinations.!##!Key points!#!• Color-coded dual-source dual-energy CT virtual noncalcium (VNCa) reconstructions derived from portal venous phase yield similar high diagnostic accuracy for the assessment of lumbar disk herniation compared to unenhanced VNCa CT series (94% vs 95%) with MRI serving as a standard of reference. • Diagnostic confidence, image quality, and noise levels differ not significantly between unenhanced and contrast-enhanced portal venous phase VNCa dual-energy CT series. • Dual-source dual-energy CT might have the potential to improve opportunistic retrospective lumbar disk herniation assessment in CT examinations performed for other indications through reconstruction of VNCa images.
1000 Sacherschließung
lokal Female [MeSH]
lokal Humans [MeSH]
lokal Computed tomography, X-ray
lokal Herniated disk
lokal Retrospective Studies [MeSH]
lokal Tomography, X-Ray Computed/methods [MeSH]
lokal Bone Marrow [MeSH]
lokal Edema [MeSH]
lokal Radiography, Dual-Energy Scanned Projection [MeSH]
lokal Virtual noncalcium reconstructions
lokal Sensitivity and Specificity [MeSH]
lokal Spine
lokal Intervertebral Disc Displacement/diagnostic imaging [MeSH]
lokal Computed Tomography
lokal Contrast agent
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S29jaCwgVml0YWxp|https://frl.publisso.de/adhoc/uri/QWxicmVjaHQsIE1vcml0eiBILg==|https://frl.publisso.de/adhoc/uri/R3J1ZW5ld2FsZCwgTGVvbiBELg==|https://frl.publisso.de/adhoc/uri/WWVsLCBJYnJhaGlt|https://frl.publisso.de/adhoc/uri/RWljaGxlciwgS2F0cmlu|https://frl.publisso.de/adhoc/uri/R3J1YmVyLVJvdWgsIFRhdGphbmE=|https://frl.publisso.de/adhoc/uri/SGFtbWVyc3RpbmdsLCBSZW5hdGUgTS4=|https://frl.publisso.de/adhoc/uri/QnVyY2ssIElyaXM=|https://frl.publisso.de/adhoc/uri/V2ljaG1hbm4sIEp1bGlhbiBMLg==|https://frl.publisso.de/adhoc/uri/QWxpemFkZWgsIExlb25hIFMu|https://frl.publisso.de/adhoc/uri/Vm9nbCwgVGhvbWFzIEou|https://frl.publisso.de/adhoc/uri/TGVuZ2EsIEx1a2Fz|https://frl.publisso.de/adhoc/uri/TWFkZXIsIENocmlzdG9waA==|https://frl.publisso.de/adhoc/uri/TWFydGluLCBTaW1vbiBTLg==|https://frl.publisso.de/adhoc/uri/TWF6emlvdHRpLCBTaWx2aW8=|https://frl.publisso.de/adhoc/uri/ROKAmUFuZ2VsbywgVG9tbWFzbw==|https://orcid.org/0000-0002-1052-7389
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1000 Erstellt am 2023-05-11T12:27:46.257+0200
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