Diagnostic reference levels and median doses for common clinical indications of CT: findings from an international registry

  1. Bos, Denise ORCID logo
  2. Yu, Sophronia
  3. Luong, Jason
  4. Chu, Philip
  5. Wang, Yifei
  6. Einstein, Andrew J.
  7. Starkey, Jay
  8. Delman, Bradley N.
  9. Duong, Phuong-Anh T.
  10. Das, Marco
  11. Schindera, Sebastian
  12. Goode, Allen R.
  13. MacLeod, Fiona
  14. Wetter, Axel
  15. Neill, Rebecca
  16. Lee, Ryan K.
  17. Roehm, Jodi
  18. Seibert, James A.
  19. Cervantes, Luisa F.
  20. Kasraie, Nima
  21. Pike, Pavlina
  22. Pahwa, Anokh
  23. Jeukens, Cécile R. L. P. N.
  24. Smith-Bindman, Rebecca

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1000 Titel
  • Diagnostic reference levels and median doses for common clinical indications of CT: findings from an international registry
1000 Autor/in
  1. Bos, Denise |
  2. Yu, Sophronia |
  3. Luong, Jason |
  4. Chu, Philip |
  5. Wang, Yifei |
  6. Einstein, Andrew J. |
  7. Starkey, Jay |
  8. Delman, Bradley N. |
  9. Duong, Phuong-Anh T. |
  10. Das, Marco |
  11. Schindera, Sebastian |
  12. Goode, Allen R. |
  13. MacLeod, Fiona |
  14. Wetter, Axel |
  15. Neill, Rebecca |
  16. Lee, Ryan K. |
  17. Roehm, Jodi |
  18. Seibert, James A. |
  19. Cervantes, Luisa F. |
  20. Kasraie, Nima |
  21. Pike, Pavlina |
  22. Pahwa, Anokh |
  23. Jeukens, Cécile R. L. P. N. |
  24. Smith-Bindman, Rebecca |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-10-13
1000 Erschienen in
1000 Quellenangabe
  • 32(3):1971-1982
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00330-021-08266-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831291/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Ob jectives!#!The European Society of Radiology identified 10 common indications for computed tomography (CT) as part of the European Study on Clinical Diagnostic Reference Levels (DRLs, EUCLID), to help standardize radiation doses. The objective of this study is to generate DRLs and median doses for these indications using data from the UCSF CT International Dose Registry.!##!Methods!#!Standardized data on 3.7 million CTs in adults were collected between 2016 and 2019 from 161 institutions across seven countries (United States of America (US), Switzerland, Netherlands, Germany, UK, Israel, Japan). DRLs (75th percentile) and median doses for volumetric CT-dose index (CTDI!##!Results!#!The number of CT scans within EUCLID categories ranged from 8,933 (HCC) to over 1.2 million (stroke). There was greater variation in dose between categories than within categories (p < .001), and doses were significantly different between categories within anatomic areas. DRLs and median doses were assessed for all categories. DRLs were higher in the US for 9 of the 10 indications (except chronic sinusitis) than in Europe but with a significantly higher sample size in the US.!##!Conclusions!#!DRLs for CTDI!##!Key points!#!• Registry data were used to create benchmarks for 10 common indications for CT identified by the European Society of Radiology. • Observed US radiation doses were higher than European for 9 of 10 indications (except chronic sinusitis). • The presented diagnostic reference levels and median doses highlight potentially unnecessary variation in radiation dose.
1000 Sacherschließung
lokal Registries
lokal Reference Values [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Adult
lokal Tomography, X-Ray Computed [MeSH]
lokal United States
lokal Diagnostic reference levels
lokal Carcinoma, Hepatocellular [MeSH]
lokal Computed Tomography
lokal Diagnostic Reference Levels [MeSH]
lokal Tomography, X-ray computed
lokal Liver Neoplasms [MeSH]
lokal Radiation Dosage [MeSH]
lokal Registries [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-9585-9787|https://frl.publisso.de/adhoc/uri/WXUsIFNvcGhyb25pYQ==|https://frl.publisso.de/adhoc/uri/THVvbmcsIEphc29u|https://frl.publisso.de/adhoc/uri/Q2h1LCBQaGlsaXA=|https://frl.publisso.de/adhoc/uri/V2FuZywgWWlmZWk=|https://frl.publisso.de/adhoc/uri/RWluc3RlaW4sIEFuZHJldyBKLg==|https://frl.publisso.de/adhoc/uri/U3RhcmtleSwgSmF5|https://frl.publisso.de/adhoc/uri/RGVsbWFuLCBCcmFkbGV5IE4u|https://frl.publisso.de/adhoc/uri/RHVvbmcsIFBodW9uZy1BbmggVC4=|https://frl.publisso.de/adhoc/uri/RGFzLCBNYXJjbw==|https://frl.publisso.de/adhoc/uri/U2NoaW5kZXJhLCBTZWJhc3RpYW4=|https://frl.publisso.de/adhoc/uri/R29vZGUsIEFsbGVuIFIu|https://frl.publisso.de/adhoc/uri/TWFjTGVvZCwgRmlvbmE=|https://frl.publisso.de/adhoc/uri/V2V0dGVyLCBBeGVs|https://frl.publisso.de/adhoc/uri/TmVpbGwsIFJlYmVjY2E=|https://frl.publisso.de/adhoc/uri/TGVlLCBSeWFuIEsu|https://frl.publisso.de/adhoc/uri/Um9laG0sIEpvZGk=|https://frl.publisso.de/adhoc/uri/U2VpYmVydCwgSmFtZXMgQS4=|https://frl.publisso.de/adhoc/uri/Q2VydmFudGVzLCBMdWlzYSBGLg==|https://frl.publisso.de/adhoc/uri/S2FzcmFpZSwgTmltYQ==|https://frl.publisso.de/adhoc/uri/UGlrZSwgUGF2bGluYQ==|https://frl.publisso.de/adhoc/uri/UGFod2EsIEFub2to|https://frl.publisso.de/adhoc/uri/SmV1a2VucywgQ8OpY2lsZSBSLiBMLiBQLiBOLg==|https://frl.publisso.de/adhoc/uri/U21pdGgtQmluZG1hbiwgUmViZWNjYQ==
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1000 Erstellt am 2023-05-11T12:31:38.749+0200
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