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1000 Titel
  • Use of PET-CT in diagnostic workup of periprosthetic infection of hip and knee joints: significance in detecting additional infectious focus
1000 Autor/in
  1. Roschke, E. |
  2. Kluge, T. |
  3. Stallkamp, F. |
  4. Roth, A. |
  5. Zajonz, D. |
  6. Hoffmann, K. T. |
  7. Sabri, O. |
  8. Kluge, R. |
  9. Ghanem, M. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-10-07
1000 Erschienen in
1000 Quellenangabe
  • 46(3):523-529
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00264-021-05218-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840933/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Introduction!#!The diagnosis and management of periprosthetic knee and hip infections as well as the identification and management of possible additional infectious foci is of great importance for successful therapy. This study analyses the importance of !##!Material and methods!#!A retrospective analysis of the clinical data and findings in the period from January 2008 to December 2018 was carried out. One hundred and four patients with in-hospital treatment due to PPI of a hip or knee joint were identified and included in this study. All patients underwent a standardized clinical examination and further surgical and antibiotic therapy. The reevaluation of performed PET-CTs was specifically carried out with regard to the local PPI or detection of secondary foci.!##!Results!#!PET-CT successfully verified the PPI in 84.2% of the patients. A total of 78 possible additional foci were detected in PET-CT in 56 (53.8%) of the examined patients. Predilection sites for possible secondary foci were joints (42.3%), pulmonary (15.4%), ear-nose-throat (15.4%), spine (11.5%), and the musculocutaneous tissues (11.5%). Fifty-four positive PET-CT findings were confirmed clinically with need of additional adequate treatment.!##!Conclusion!#!PET-CT is a valuable diagnostic tool to confirm periprosthetic joint infection. At the same time, the whole-body PET/CT may detect additional foci of infection with impact on subsequent treatment strategy. PET was of special value in detecting infections at distant locations far from the primary infected joint in significant number. These distant infection locations can be potential cause of a re-infection. This clearly reflects the need of their diagnosis.
1000 Sacherschließung
lokal Anti-Bacterial Agents/therapeutic use [MeSH]
lokal Knee Joint/diagnostic imaging [MeSH]
lokal Hip and knee arthroplasty
lokal Humans [MeSH]
lokal Knee Joint/surgery [MeSH]
lokal Positron Emission Tomography Computed Tomography [MeSH]
lokal Retrospective Studies [MeSH]
lokal Hip Joint/diagnostic imaging [MeSH]
lokal Arthroplasty, Replacement, Knee/adverse effects [MeSH]
lokal Prosthesis-Related Infections/diagnostic imaging [MeSH]
lokal PET-CT
lokal Arthroplasty, Replacement, Hip/adverse effects [MeSH]
lokal Original Paper
lokal Prosthesis-Related Infections/therapy [MeSH]
lokal Hip Joint/surgery [MeSH]
lokal Periprosthetic infection
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Um9zY2hrZSwgRS4=|https://frl.publisso.de/adhoc/uri/S2x1Z2UsIFQu|https://frl.publisso.de/adhoc/uri/U3RhbGxrYW1wLCBGLg==|https://frl.publisso.de/adhoc/uri/Um90aCwgQS4=|https://frl.publisso.de/adhoc/uri/WmFqb256LCBELg==|https://frl.publisso.de/adhoc/uri/SG9mZm1hbm4sIEsuIFQu|https://frl.publisso.de/adhoc/uri/U2FicmksIE8u|https://frl.publisso.de/adhoc/uri/S2x1Z2UsIFIu|https://frl.publisso.de/adhoc/uri/R2hhbmVtLCBNLg==
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1000 Erstellt am 2023-05-11T13:16:03.252+0200
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