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1000 Titel
  • Fully automated analysis combining [18F]-FET-PET and multiparametric MRI including DSC perfusion and APTw imaging: a promising tool for objective evaluation of glioma progression
1000 Autor/in
  1. Paprottka, K. J. |
  2. Kleiner, S. |
  3. Preibisch, C. |
  4. Kofler, F. |
  5. Schmidt-Graf, F. |
  6. Delbridge, C. |
  7. Bernhardt, D. |
  8. Combs, S. E. |
  9. Gempt, J. |
  10. Meyer, B. |
  11. Zimmer, C. |
  12. Menze, B. H. |
  13. Yakushev, I. |
  14. Kirschke, J. S. |
  15. Wiestler, B. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-25
1000 Erschienen in
1000 Quellenangabe
  • 48(13):4445-4455
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00259-021-05427-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566389/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!To evaluate diagnostic accuracy of fully automated analysis of multimodal imaging data using [!##!Material and methods!#!At suspected tumor progression, MRI and [!##!Results!#!In 57/74 cases (77%), tumor progression was confirmed histopathologically (39 cases) or via follow-up imaging (18 cases), while remaining 17 cases were diagnosed as treatment-related changes. The classification accuracy of the Random Forest classifier was 0.86, 95% CI 0.77-0.93 (sensitivity 0.91, 95% CI 0.81-0.97; specificity 0.71, 95% CI 0.44-0.9), significantly above the no-information rate of 0.77 (p = 0.03), and higher compared to an accuracy of 0.82 for MRI (95% CI 0.72-0.9), 0.81 for [!##!Conclusion!#!Automated, joint image analysis of [
1000 Sacherschließung
lokal Amides [MeSH]
lokal Humans [MeSH]
lokal Multiparametric MRI
lokal Retrospective Studies [MeSH]
lokal Glioma/diagnostic imaging [MeSH]
lokal DSC perfusion
lokal Kirschke
lokal J. S. and Wiestler
lokal Original Article
lokal Magnetic Resonance Imaging [MeSH]
lokal Glioma progression
lokal B. coshared last
lokal APTw
lokal Positron-Emission Tomography [MeSH]
lokal Perfusion [MeSH]
lokal Tyrosine [MeSH]
lokal Advanced Image Analyses (Radiomics and Artificial Intelligence)
lokal Protons [MeSH]
lokal Brain Neoplasms/diagnostic imaging [MeSH]
lokal [
lokal Fully automated
lokal Multiparametric Magnetic Resonance Imaging [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/UGFwcm90dGthLCBLLiBKLg==|https://frl.publisso.de/adhoc/uri/S2xlaW5lciwgUy4=|https://frl.publisso.de/adhoc/uri/UHJlaWJpc2NoLCBDLg==|https://frl.publisso.de/adhoc/uri/S29mbGVyLCBGLg==|https://frl.publisso.de/adhoc/uri/U2NobWlkdC1HcmFmLCBGLg==|https://frl.publisso.de/adhoc/uri/RGVsYnJpZGdlLCBDLg==|https://frl.publisso.de/adhoc/uri/QmVybmhhcmR0LCBELg==|https://frl.publisso.de/adhoc/uri/Q29tYnMsIFMuIEUu|https://frl.publisso.de/adhoc/uri/R2VtcHQsIEou|https://frl.publisso.de/adhoc/uri/TWV5ZXIsIEIu|https://frl.publisso.de/adhoc/uri/WmltbWVyLCBDLg==|https://frl.publisso.de/adhoc/uri/TWVuemUsIEIuIEgu|https://frl.publisso.de/adhoc/uri/WWFrdXNoZXYsIEku|https://frl.publisso.de/adhoc/uri/S2lyc2Noa2UsIEouIFMu|https://frl.publisso.de/adhoc/uri/V2llc3RsZXIsIEIu
1000 Hinweis
  • DeepGreen-ID: 34db90bd653b4565933ce82a4f8465ec ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-05-11T13:44:43.560+0200
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