Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients

  1. Giesel, Frederik L.
  2. Kratochwil, Clemens
  3. Schlittenhardt, Joel
  4. Dendl, Katharina
  5. Eiber, Matthias
  6. Staudinger, Fabian
  7. Kessler, Lukas
  8. Fendler, Wolfgang P.
  9. Lindner, Thomas
  10. Koerber, Stefan A.
  11. Cardinale, Jens
  12. Sennung, David
  13. Roehrich, Manuel
  14. Debus, Juergen
  15. Sathekge, Mike
  16. Haberkorn, Uwe
  17. Calais, Jeremie
  18. Serfling, Sebastian
  19. Buck, Andreas L.

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1000 Titel
  • Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients
1000 Autor/in
  1. Giesel, Frederik L. |
  2. Kratochwil, Clemens |
  3. Schlittenhardt, Joel |
  4. Dendl, Katharina |
  5. Eiber, Matthias |
  6. Staudinger, Fabian |
  7. Kessler, Lukas |
  8. Fendler, Wolfgang P. |
  9. Lindner, Thomas |
  10. Koerber, Stefan A. |
  11. Cardinale, Jens |
  12. Sennung, David |
  13. Roehrich, Manuel |
  14. Debus, Juergen |
  15. Sathekge, Mike |
  16. Haberkorn, Uwe |
  17. Calais, Jeremie |
  18. Serfling, Sebastian |
  19. Buck, Andreas L. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-17
1000 Erschienen in
1000 Quellenangabe
  • 48(13):4377-4385
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00259-021-05307-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566651/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!FAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The purpose of this study is the head-to-head intra-individual comparison of !##!Material and methods!#!This international retrospective multicenter analysis included PET/CT data from 71 patients from 6 centers who underwent both !##!Results!#!A total of 71 patients were studied of, which 28 were female and 43 male (median age 60). In 41 of 71 patients, the primary tumor was present. Forty-three of 71 patients exhibited 162 metastatic lesions. !##!Conclusion!#!Quantitative tumor uptake is comparable between
1000 Sacherschließung
lokal Female [MeSH]
lokal Humans [MeSH]
lokal Various cancer diseases
lokal FDG PET/CT
lokal Positron Emission Tomography Computed Tomography [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal FAPI PET/CT
lokal Neoplasms/diagnostic imaging [MeSH]
lokal Fluorodeoxyglucose F18 [MeSH]
lokal Original Article
lokal Gallium Radioisotopes [MeSH]
lokal Male [MeSH]
lokal Tissue Distribution [MeSH]
lokal Oncology – General
lokal Cancer-associated fibroblast
1000 Liste der Beteiligten
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1000 Erstellt am 2023-05-11T13:51:49.652+0200
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