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1000
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Abstract/Summary
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The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the workplace (MAK value) for 2‐methoxypropylacetate‐1 [70657‐70‐4]. Available publications and unpublished study reports are described in detail. Critical effects of 2‐methoxypropylacetate‐1 are its irritancy and teratogenicity. A MAK value of 5 ml/m3 had been set. This value is now reaffirmed based on the findings on the irritancy of the substance in a 28‐day inhalation study with rats. Since a local effect is critical, Peak Limitation Category I with excursion factor of 2 has been set. 2‐Methoxypropylacetate‐1 remains assigned to Pregnancy Risk Group B and it also remains designated with an “H” (for substances that can be absorbed through the skin in toxicologically relevant amounts).
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