Universal selenium nanoadjuvant with immunopotentiating and redox-shaping activities inducing high-quality immunity for SARS-CoV-2 vaccine

  1. Lai, Haoqiang
  2. Xu, Ligeng
  3. Liu, Chang
  4. Shi, Sujiang
  5. Jiang, Yalin
  6. Yu, Yangyang
  7. Deng, Bo
  8. Chen, Tianfeng

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WeightNameValue
1000 Titel
  • Universal selenium nanoadjuvant with immunopotentiating and redox-shaping activities inducing high-quality immunity for SARS-CoV-2 vaccine
1000 Autor/in
  1. Lai, Haoqiang |
  2. Xu, Ligeng |
  3. Liu, Chang |
  4. Shi, Sujiang |
  5. Jiang, Yalin |
  6. Yu, Yangyang |
  7. Deng, Bo |
  8. Chen, Tianfeng |
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-02-27
1000 Erschienen in
1000 Quellenangabe
  • 8(1):88
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41392-023-01371-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969362/ |
1000 Ergänzendes Material
  • https://www.nature.com/articles/s41392-023-01371-1#Sec1 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The COVID-19 pandemic still greatly threatens the public health worldwide and novel vaccines to highly effectively combat SARS-CoV-2 remains an unmet clinical need. However, redox imbalance in immune cells under extra stimulation by vaccine or pathogens greatly dampens the quality of the induced immunity.1 In addition, people infected with COVID-19 that characterized by immune system malfunction were also approved to be attributed by the robust oxidative stress,2 indicating the crucial roles of regulation of redox balance in the metabolic rewiring of immune cells and its activation. Therefore, the development of novel vaccines with redox regulation and superior immuno-potentiating properties to combat against SARS-CoV-2 will be greatly desired.
1000 Sacherschließung
lokal Infectious diseases
lokal Drug delivery
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TGFpLCBIYW9xaWFuZw==|https://frl.publisso.de/adhoc/uri/WHUsIExpZ2VuZw==|https://frl.publisso.de/adhoc/uri/TGl1LCBDaGFuZw==|https://frl.publisso.de/adhoc/uri/U2hpLCBTdWppYW5n|https://frl.publisso.de/adhoc/uri/SmlhbmcsIFlhbGlu|https://frl.publisso.de/adhoc/uri/WXUsIFlhbmd5YW5n|https://frl.publisso.de/adhoc/uri/RGVuZywgQm8=|https://frl.publisso.de/adhoc/uri/Q2hlbiwgVGlhbmZlbmc=
1000 Label
1000 Förderer
  1. National Natural Science Foundation of China |
  2. National Science Fund for Distinguished Young Scholars |
  3. University Innovation team project of Guangdong Province |
  4. Natural Science Major Project of Guangdong Province |
  5. Basic and Applied Basic Research Foundation of Guangdong Province |
  6. Basic and Applied Basic Research Project of Guangzhou |
  7. China Postdoctoral Science Foundation |
1000 Fördernummer
  1. 21877049—T.C.;32171296—T.C.;31871006—L.X.;32101044—H.L.
  2. 82225025—T.C.
  3. 2019KCXTD008
  4. 2019KZDXM029
  5. 2021B1515020018—L.X.;2020B1515120043—T.C.
  6. 202002030272—L.X.
  7. 2020M681372
1000 Förderprogramm
  1. -
  2. -
  3. -
  4. -
  5. -
  6. -
  7. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer National Natural Science Foundation of China |
    1000 Förderprogramm -
    1000 Fördernummer 21877049—T.C.;32171296—T.C.;31871006—L.X.;32101044—H.L.
  2. 1000 joinedFunding-child
    1000 Förderer National Science Fund for Distinguished Young Scholars |
    1000 Förderprogramm -
    1000 Fördernummer 82225025—T.C.
  3. 1000 joinedFunding-child
    1000 Förderer University Innovation team project of Guangdong Province |
    1000 Förderprogramm -
    1000 Fördernummer 2019KCXTD008
  4. 1000 joinedFunding-child
    1000 Förderer Natural Science Major Project of Guangdong Province |
    1000 Förderprogramm -
    1000 Fördernummer 2019KZDXM029
  5. 1000 joinedFunding-child
    1000 Förderer Basic and Applied Basic Research Foundation of Guangdong Province |
    1000 Förderprogramm -
    1000 Fördernummer 2021B1515020018—L.X.;2020B1515120043—T.C.
  6. 1000 joinedFunding-child
    1000 Förderer Basic and Applied Basic Research Project of Guangzhou |
    1000 Förderprogramm -
    1000 Fördernummer 202002030272—L.X.
  7. 1000 joinedFunding-child
    1000 Förderer China Postdoctoral Science Foundation |
    1000 Förderprogramm -
    1000 Fördernummer 2020M681372
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6462281.rdf
1000 Erstellt am 2023-11-03T11:00:40.259+0100
1000 Erstellt von 337
1000 beschreibt frl:6462281
1000 Bearbeitet von 317
1000 Zuletzt bearbeitet Mon Nov 06 10:44:08 CET 2023
1000 Objekt bearb. Mon Nov 06 10:43:56 CET 2023
1000 Vgl. frl:6462281
1000 Oai Id
  1. oai:frl.publisso.de:frl:6462281 |
1000 Sichtbarkeit Metadaten public
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