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1000 Titel
  • Frequently assessed and used prognostic factors for outcome after macular hole surgery: which is better?
1000 Autor/in
  1. Roth, M. |
  2. Schön, N. |
  3. Jürgens, L. |
  4. Engineer, D. |
  5. Kirchhoff, K. |
  6. Guthoff, R. |
  7. Schmidt, J. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-18
1000 Erschienen in
1000 Quellenangabe
  • 21(1):398
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12886-021-02164-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600723/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The aim of this retrospective study was to evaluate commonly used clinical and OCT-morphological parameters, including perifoveal pseudocysts, as prognostic factors for postoperative outcome after macular hole surgery in a retinal referral clinic in North Rhine-Westphalia, Germany.!##!Methods and material!#!This was a retrospective analysis of all patients who underwent surgery because of idiopathic MH between 2011 and 2017 in Augenklinik Tausendfensterhaus, Duisburg, Germany. Statistical evaluation of clinical and OCT-based parameters, including the areas of intraretinal pseudocysts, was conducted. The main statistical outcomes were surgical success and visual acuity. Only parameters with a highly significant correlation to the outcome parameters (postoperative visual acuity (VA); surgical success) in univariate analysis were entered in linear and logistic regression analyses.!##!Results!#!A total of 189 eyes of 178 patients (71.4% female; mean age 67.5 ± 8.2 a) who underwent surgery because of MH were included. The overall closure rate was 86.8%. The mean best corrected VA increased from 0.7 ± 0.3 logMAR before surgery to 0.5 ± 0.3 logMAR (p < 0.0001). While several clinical and OCT-based parameters as well as calculated indices showed a significant correlation with the outcome measures, the regression analysis showed that the minimum linear diameter was the only parameter that both predicted surgical success (p = 0.015) and was correlated with postoperative VA (p < 0.001).!##!Conclusion!#!The minimum linear diameter serves as an easily assessed prognostic factor with the best predictive properties. This result is of great importance for clinical practice, as it simplifies the postsurgical prognosis.
1000 Sacherschließung
lokal Female [MeSH]
lokal Vitrectomy [MeSH]
lokal Macular hole
lokal Aged [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Vitreoretinal surgery
lokal Prognostic parameters
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Tomography, Optical Coherence [MeSH]
lokal Retinal Perforations/surgery [MeSH]
lokal Vitrectomy
lokal Optical coherence tomography
lokal Male [MeSH]
lokal Research
lokal Prognosis [MeSH]
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  1. https://frl.publisso.de/adhoc/uri/Um90aCwgTS4=|https://frl.publisso.de/adhoc/uri/U2Now7ZuLCBOLg==|https://frl.publisso.de/adhoc/uri/SsO8cmdlbnMsIEwu|https://frl.publisso.de/adhoc/uri/RW5naW5lZXIsIEQu|https://frl.publisso.de/adhoc/uri/S2lyY2hob2ZmLCBLLg==|https://frl.publisso.de/adhoc/uri/R3V0aG9mZiwgUi4=|https://frl.publisso.de/adhoc/uri/U2NobWlkdCwgSi4=
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1000 Erstellt am 2023-11-15T12:15:16.426+0100
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