The African Network for Improved Diagnostics, Epidemiology and Management of common infectious Agents

  1. Schubert, Grit ORCID logo
  2. Achi, Vincent
  3. Ahuka, Steve
  4. Belarbi, Essia
  5. Bourhaima, Ouattara
  6. Eckmanns, Tim
  7. Johnstone, Siobhan
  8. Kabore, Firmin
  9. Kra, Ouffoue
  10. Mendes, Adriano
  11. Ouedraogo, Abdoul-Salam
  12. Poda, Armel
  13. Some, Arsène Satouro
  14. Tomczyk, Sara
  15. Couacy-Hymann, Emmanuel
  16. Kayembe, Jean-Marie
  17. Meda, Nicolas
  18. Muyembe Tamfum, Jean-Jacques
  19. Ouangraoua, Soumeya
  20. Page, Nicola
  21. Venter, Marietjie
  22. Leendertz, Fabian H.
  23. Akoua-Koffi, Chantal
  24. Kouadio, Vincent Assé
  25. Aka-Tano, Aude
  26. Diarrassouba, Adoulaye
  27. Anoh, Etilé
  28. Traoré, Adjaratou
  29. Sounan, Fidèle Touré
  30. Karidioula, Safiatou
  31. Kizito, Gabriel Mbunsu
  32. Izizag, Benilde Bepouka
  33. Mpwekela, Nicole
  34. Kabengele, Benoit
  35. Alama, Nicole
  36. Tshiani, Olivier
  37. Lusamaki, Eddy Kinganda
  38. Muyembe, Baby
  39. Mitongo, Naomie
  40. Manienga, John
  41. Lionzo, Franck
  42. Mbandu, Alliance
  43. Makiala, Sheila
  44. Sin, Muna Abu
  45. Gröschner, Karin
  46. Köhler, Susanne
  47. Niendorf, Sandra
  48. Nowak, Kathrin
  49. Pitzinger, Paul
  50. Sachse, Andreas
  51. Vietor, Ann Christin
  52. Thomas, Juno
  53. Walaza, Sibongile
  54. de Gouvea, Linda
  55. von Mollendorf, Claire
  56. Quan, Vanessa
  57. Keddy, Karen
  58. Smith, Anthony
  59. Ramalwa, Ntsieni
  60. Avenant, Theunis
  61. du Plessis, Nicolette
  62. Menu, Kgothatso
  63. Pretorius, Marthi
  64. McIntyre, Caitlyn
  65. Bonnet, Elise
  66. Jeal, Rebecca

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1000 Titel
  • The African Network for Improved Diagnostics, Epidemiology and Management of common infectious Agents
1000 Autor/in
  1. Schubert, Grit |
  2. Achi, Vincent |
  3. Ahuka, Steve |
  4. Belarbi, Essia |
  5. Bourhaima, Ouattara |
  6. Eckmanns, Tim |
  7. Johnstone, Siobhan |
  8. Kabore, Firmin |
  9. Kra, Ouffoue |
  10. Mendes, Adriano |
  11. Ouedraogo, Abdoul-Salam |
  12. Poda, Armel |
  13. Some, Arsène Satouro |
  14. Tomczyk, Sara |
  15. Couacy-Hymann, Emmanuel |
  16. Kayembe, Jean-Marie |
  17. Meda, Nicolas |
  18. Muyembe Tamfum, Jean-Jacques |
  19. Ouangraoua, Soumeya |
  20. Page, Nicola |
  21. Venter, Marietjie |
  22. Leendertz, Fabian H. |
  23. Akoua-Koffi, Chantal |
  24. Kouadio, Vincent Assé |
  25. Aka-Tano, Aude |
  26. Diarrassouba, Adoulaye |
  27. Anoh, Etilé |
  28. Traoré, Adjaratou |
  29. Sounan, Fidèle Touré |
  30. Karidioula, Safiatou |
  31. Kizito, Gabriel Mbunsu |
  32. Izizag, Benilde Bepouka |
  33. Mpwekela, Nicole |
  34. Kabengele, Benoit |
  35. Alama, Nicole |
  36. Tshiani, Olivier |
  37. Lusamaki, Eddy Kinganda |
  38. Muyembe, Baby |
  39. Mitongo, Naomie |
  40. Manienga, John |
  41. Lionzo, Franck |
  42. Mbandu, Alliance |
  43. Makiala, Sheila |
  44. Sin, Muna Abu |
  45. Gröschner, Karin |
  46. Köhler, Susanne |
  47. Niendorf, Sandra |
  48. Nowak, Kathrin |
  49. Pitzinger, Paul |
  50. Sachse, Andreas |
  51. Vietor, Ann Christin |
  52. Thomas, Juno |
  53. Walaza, Sibongile |
  54. de Gouvea, Linda |
  55. von Mollendorf, Claire |
  56. Quan, Vanessa |
  57. Keddy, Karen |
  58. Smith, Anthony |
  59. Ramalwa, Ntsieni |
  60. Avenant, Theunis |
  61. du Plessis, Nicolette |
  62. Menu, Kgothatso |
  63. Pretorius, Marthi |
  64. McIntyre, Caitlyn |
  65. Bonnet, Elise |
  66. Jeal, Rebecca |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-07
1000 Erschienen in
1000 Quellenangabe
  • 21(1):539
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12879-021-06238-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184052/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!In sub-Saharan Africa, acute respiratory infections (ARI), acute gastrointestinal infections (GI) and acute febrile disease of unknown cause (AFDUC) have a large disease burden, especially among children, while respective aetiologies often remain unresolved. The need for robust infectious disease surveillance to detect emerging pathogens along with common human pathogens has been highlighted by the ongoing novel coronavirus disease 2019 (COVID-19) pandemic. The African Network for Improved Diagnostics, Epidemiology and Management of Common Infectious Agents (ANDEMIA) is a sentinel surveillance study on the aetiology and clinical characteristics of ARI, GI and AFDUC in sub-Saharan Africa.!##!Methods!#!ANDEMIA includes 12 urban and rural health care facilities in four African countries (Côte d'Ivoire, Burkina Faso, Democratic Republic of the Congo and Republic of South Africa). It was piloted in 2018 in Côte d'Ivoire and the initial phase will run from 2019 to 2021. Case definitions for ARI, GI and AFDUC were established, as well as syndrome-specific sampling algorithms including the collection of blood, naso- and oropharyngeal swabs and stool. Samples are tested using comprehensive diagnostic protocols, ranging from classic bacteriology and antimicrobial resistance screening to multiplex real-time polymerase chain reaction (PCR) systems and High Throughput Sequencing. In March 2020, PCR testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and analysis of full genomic information was included in the study. Standardised questionnaires collect relevant clinical, demographic, socio-economic and behavioural data for epidemiologic analyses. Controls are enrolled over a 12-month period for a nested case-control study. Data will be assessed descriptively and aetiologies will be evaluated using a latent class analysis among cases. Among cases and controls, an integrated analytic approach using logistic regression and Bayesian estimation will be employed to improve the assessment of aetiology and associated risk factors.!##!Discussion!#!ANDEMIA aims to expand our understanding of ARI, GI and AFDUC aetiologies in sub-Saharan Africa using a comprehensive laboratory diagnostics strategy. It will foster early detection of emerging threats and continued monitoring of important common pathogens. The network collaboration will be strengthened and site diagnostic capacities will be reinforced to improve quality management and patient care.
1000 Sacherschließung
gnd 1206347392 COVID-19
lokal Antimicrobial resistance
lokal Sentinel Surveillance [MeSH]
lokal South Africa [MeSH]
lokal Bayes Theorem [MeSH]
lokal Aetiologies
lokal Fever/epidemiology [MeSH]
lokal Burkina Faso [MeSH]
lokal Sentinel surveillance
lokal Acute febrile disease of unknown cause
lokal Case-Control Studies [MeSH]
lokal Outbreak detection
lokal Sub-Saharan Africa
lokal SARS-CoV-2
lokal Gastrointestinal Diseases/microbiology [MeSH]
lokal Fever/microbiology [MeSH]
lokal Study Protocol
lokal Humans [MeSH]
lokal COVID-19
lokal Healthcare-associated infection control
lokal Acute gastrointestinal infections
lokal Respiratory Tract Infections/epidemiology [MeSH]
lokal Mass Screening [MeSH]
lokal Gastrointestinal Diseases/epidemiology [MeSH]
lokal Cote d'Ivoire [MeSH]
lokal Acute respiratory tract infections
lokal Democratic Republic of the Congo [MeSH]
lokal Communicable Diseases/epidemiology [MeSH]
lokal Communicable Diseases/diagnosis [MeSH]
lokal Real-Time Polymerase Chain Reaction [MeSH]
1000 Liste der Beteiligten
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1000 Erstellt am 2023-11-15T17:33:51.078+0100
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1000 Zuletzt bearbeitet Thu Nov 30 21:19:55 CET 2023
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