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1000 Titel
  • Geometric changes in aortic root replacement using Freestyle prosthesis
1000 Autor/in
  1. Osswald, Anja |
  2. Zubarevich, Alina |
  3. Rad, Arian Arjomandi |
  4. Vardanyan, Robert |
  5. Zhigalov, Konstantin |
  6. Wendt, Daniel |
  7. Schmack, Bastian |
  8. Mashhour, Ahmed |
  9. Ruhparwar, Arjang |
  10. Weymann, Alexander |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-28
1000 Erschienen in
1000 Quellenangabe
  • 16(1):204
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13019-021-01583-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8320201/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The Medtronic Freestyle prosthesis has proven to be a promising recourse for aortic root replacement in various indications. The present study aims to evaluate clinical outcomes and geometric changes of the aorta after Freestyle implantation.!##!Methods!#!Between October 2005 and November 2020, the computed tomography angiography (CTA) data of 32 patients were analyzed in a cohort of 68 patients that underwent aortic root replacement using Freestyle prosthesis. The minimum and maximum diameters and areas of the aortic annulus, aortic root, ascending aorta, and the proximal aortic arch were measured at a plane perpendicular to the long axis of the aorta using 3D multiplanar reconstruction in both the preoperative (n = 32) and postoperative (n = 10) CTAs. Moreover, volumetric changes of the aortic root and ascending aorta were quantified.!##!Results!#!Mean age was 64.6 ± 10.6 years. Indications for surgery using Freestyle prosthesis were combined aortic valve pathologies, aortic aneurysm or dissection, and endocarditis, with concomitant surgery occurring in 28 out of 32 patients. In-hospital mortality was 18.6%. Preoperative diameter and area measurements of the aortic annulus strongly correlated with the implanted valve size (p < 0.001). Bicuspid valve was present in 28.1% of the patients. Diameter and areas of the aortic root decreased after freestyle implantation, resulting in a reduction of the aortic root volume (45.6 ± 26.3 cm!##!Conclusion!#!Implantation of the Freestyle prosthesis presents excellent results in restoring the aortic geometry. Preoperative CTA measurements are beneficial to the surgical procedure and valve selection and therefore, if available, should be considered in pre-operative planning.
1000 Sacherschließung
lokal Female [MeSH]
lokal Aorta/surgery [MeSH]
lokal Ventricular Function, Left [MeSH]
lokal Heart Valve Prosthesis Implantation [MeSH]
lokal Aortic Valve/diagnostic imaging [MeSH]
lokal Aged [MeSH]
lokal Computed tomography measurement
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Aortic Valve/surgery [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Percutaneous Coronary Intervention [MeSH]
lokal Heart Valve Prosthesis [MeSH]
lokal Male [MeSH]
lokal Stroke Volume [MeSH]
lokal Bioroot
lokal Bioprosthesis [MeSH]
lokal Research Article
lokal Aortic root
lokal Aortic valve replacement
lokal Prosthesis Design [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-2315-880X|https://frl.publisso.de/adhoc/uri/WnViYXJldmljaCwgQWxpbmE=|https://frl.publisso.de/adhoc/uri/UmFkLCBBcmlhbiBBcmpvbWFuZGk=|https://frl.publisso.de/adhoc/uri/VmFyZGFueWFuLCBSb2JlcnQ=|https://frl.publisso.de/adhoc/uri/WmhpZ2Fsb3YsIEtvbnN0YW50aW4=|https://frl.publisso.de/adhoc/uri/V2VuZHQsIERhbmllbA==|https://frl.publisso.de/adhoc/uri/U2NobWFjaywgQmFzdGlhbg==|https://frl.publisso.de/adhoc/uri/TWFzaGhvdXIsIEFobWVk|https://frl.publisso.de/adhoc/uri/UnVocGFyd2FyLCBBcmphbmc=|https://frl.publisso.de/adhoc/uri/V2V5bWFubiwgQWxleGFuZGVy
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1000 Erstellt am 2023-11-15T19:19:23.013+0100
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