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1000 Titel
  • Melkersson–Rosenthal syndrome in the context of sarcoidosis: a case report 
1000 Autor/in
  1. Casper, J. |
  2. Mohammad-Khani, S. |
  3. Schmidt, J. J. |
  4. Kielstein, J. T. |
  5. Lenarz, T. |
  6. Haller, H. |
  7. Wagner, Annette D. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-10-04
1000 Erschienen in
1000 Quellenangabe
  • 15(1):488
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13256-021-03044-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489098/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Melkersson-Rosenthal syndrome is a rare disease characterized by the triad of recurrent orofacial swelling with facial paralysis and fissured dorsal tongue. Histologically, noncaseating granulomatous inflammation occurs that confirms the diagnosis. Overlaps between granulomatous diseases such as sarcoidosis and Crohn's disease are described. Systemic corticosteroid therapy is the treatment of choice for acute attacks.!##!Case presentation!#!We here present a case of a 59-year-old White woman suffering from Melkersson-Rosenthal syndrome with a past history of sarcoidosis on therapy with leflunomide in combination with low-dose tacrolimus successfully treated with the anti-leprosy drug clofazimine after failure of systemic steroid therapy.!##!Conclusions!#!We propose clofazimine as an alternative treatment in steroid-refractory cases.
1000 Sacherschließung
lokal Female [MeSH]
lokal Crohn Disease [MeSH]
lokal Sarcoidosis/drug therapy [MeSH]
lokal Humans [MeSH]
lokal Facial Paralysis [MeSH]
lokal Melkersson-Rosenthal Syndrome/complications [MeSH]
lokal Case report
lokal Middle Aged [MeSH]
lokal Sarcoidosis/diagnosis [MeSH]
lokal Sarcoidosis/complications [MeSH]
lokal Melkersson-Rosenthal Syndrome/diagnosis [MeSH]
lokal Clofazimine
lokal Melkersson–Rosenthal syndrome
lokal Behavior Therapy [MeSH]
lokal Case Report
lokal Melkersson-Rosenthal Syndrome/drug therapy [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Q2FzcGVyLCBKLg==|https://frl.publisso.de/adhoc/uri/TW9oYW1tYWQtS2hhbmksIFMu|https://frl.publisso.de/adhoc/uri/U2NobWlkdCwgSi4gSi4=|https://frl.publisso.de/adhoc/uri/S2llbHN0ZWluLCBKLiBULg==|https://frl.publisso.de/adhoc/uri/TGVuYXJ6LCBULg==|https://frl.publisso.de/adhoc/uri/SGFsbGVyLCBILg==|https://frl.publisso.de/adhoc/uri/V2FnbmVyLCBBbm5ldHRlIEQu
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