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1000 Titel
  • EuroScore and IL-6 predict the course in ICU after cardiac surgery
1000 Autor/in
  1. Bauer, Andreas |
  2. Korten, Insa |
  3. Juchem, Gerd |
  4. Kiesewetter, Isabel |
  5. Kilger, Erich |
  6. Heyn, Jens |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-03-26
1000 Erschienen in
1000 Quellenangabe
  • 26(1):29
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40001-021-00501-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995398/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Despite modern advances in intensive care medicine and surgical techniques, mortality rates in cardiac surgical patients are still about 3%. Considerable efforts were made to predict morbidity and mortality after cardiac surgery. In this study, we analysed the predictive properties of EuroScore and IL-6 for mortality in ICU, prolonged postoperative mechanical ventilation, and prolonged stay in ICU.!##!Methods!#!We enrolled 2972 patients undergoing cardiac surgery. The patients either underwent aortic valve surgery (AV), mitral valve surgery (MV), coronary artery bypass grafting (CABG), and combined operations of aortic valve and coronary artery bypass grafting (AV + CABG) or of mitral and tricuspid valve (MV + TV). Different laboratory and clinical parameters were analysed.!##!Results!#!EuroScore as well as IL-6 were associated with increased mortality after cardiac surgery. Furthermore, a higher EuroScore and elevated levels of IL-6 were predictors for prolonged mechanical ventilation and a longer stay in ICU. Especially, highly significant elevated IL-6 levels and an increased EuroScore showed a strong association. Statistics suggested superiority when both parameters were combined in a single model.!##!Conclusion!#!Our results suggest that EuroScore and IL-6 are helpful in predicting the course in ICU after cardiac surgery, and therefore, the use of intensive care resources. Especially, the combination of highly elevated levels of IL-6 and EuroScore may prove to be excellent predictors for an unfortunate postoperative course in ICU.
1000 Sacherschließung
lokal Length of Stay/statistics
lokal Aged [MeSH]
lokal Cardiac Surgical Procedures [MeSH]
lokal Postoperative Complications/epidemiology [MeSH]
lokal Germany/epidemiology [MeSH]
lokal Male [MeSH]
lokal Intensive Care Units [MeSH]
lokal Risk Assessment/methods [MeSH]
lokal IL-6
lokal Female [MeSH]
lokal Outcome
lokal Follow-Up Studies [MeSH]
lokal EuroScore
lokal Biomarkers/blood [MeSH]
lokal Humans [MeSH]
lokal Intensive care medicine
lokal Cardiovascular Diseases/surgery [MeSH]
lokal Incidence [MeSH]
lokal Predictive Value of Tests [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Time Factors [MeSH]
lokal Research
lokal Postoperative Complications/blood [MeSH]
lokal Prognosis [MeSH]
lokal Interleukin-6/blood [MeSH]
lokal Cardiac surgery
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QmF1ZXIsIEFuZHJlYXM=|https://frl.publisso.de/adhoc/uri/S29ydGVuLCBJbnNh|https://frl.publisso.de/adhoc/uri/SnVjaGVtLCBHZXJk|https://frl.publisso.de/adhoc/uri/S2llc2V3ZXR0ZXIsIElzYWJlbA==|https://frl.publisso.de/adhoc/uri/S2lsZ2VyLCBFcmljaA==|https://frl.publisso.de/adhoc/uri/SGV5biwgSmVucw==
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  1. EuroScore and IL-6 predict the course in ICU after cardiac surgery
1000 Objektart article
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1000 @id frl:6464383.rdf
1000 Erstellt am 2023-11-16T03:17:47.971+0100
1000 Erstellt von 322
1000 beschreibt frl:6464383
1000 Zuletzt bearbeitet Thu Nov 30 23:46:59 CET 2023
1000 Objekt bearb. Thu Nov 30 23:46:59 CET 2023
1000 Vgl. frl:6464383
1000 Oai Id
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