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1000 Titel
  • Predicting EQ-5D-5L crosswalk from the PROMIS-29 profile for the United Kingdom, France, and Germany
1000 Autor/in
  1. Klapproth, Christoph Paul |
  2. van Bebber, J. |
  3. Sidey-Gibbons, C. J. |
  4. Valderas, J. M. |
  5. Leplege, A. |
  6. Rose, M. |
  7. Fischer, F. |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-12-17
1000 Erschienen in
1000 Quellenangabe
  • 18(1):389
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12955-020-01629-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745375/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background: EQ-5D health state utilities (HSU) are commonly used in health economics to compute quality-adjusted life years (QALYs). The EQ-5D, which is country-specific, can be derived directly or by mapping from self-reported health-related quality of life (HRQoL) scales such as the PROMIS-29 profile. The PROMIS-29 from the Patient Reported Outcome Measures Information System is a comprehensive assessment of self-reported health with excellent psychometric properties. We sought to find optimal models predicting the EQ-5D-5L crosswalk from the PROMIS-29 in the United Kingdom, France, and Germany and compared the prediction performances with that of a US model. Methods: We collected EQ-5D-5L and PROMIS-29 profiles and three samples representative of the general populations in the UK (n = 1509), France (n = 1501), and Germany (n = 1502). We used stepwise regression with backward selection to find the best models to predict the EQ-5D-5L crosswalk from all seven PROMIS-29 domains. We investigated the agreement between the observed and predicted EQ-5D-5L crosswalk in all three countries using various indices for the prediction performance, including Bland-Altman plots to examine the performance along the HSU continuum. Results: The EQ-5D-5L crosswalk was best predicted in France (nRMSEFRA = 0.075, nMAEFRA = 0.052), followed by the UK (nRMSEUK = 0.076, nMAEUK = 0.053) and Germany (nRMSEGER = 0.079, nMAEGER = 0.051). The Bland-Altman plots show that the inclusion of higher-order effects reduced the overprediction of low HSU scores. Conclusions: Our models provide a valid method to predict the EQ-5D-5L crosswalk from the PROMIS-29 for the UK, France, and Germany.
1000 Sacherschließung
lokal Quality of Life Research
lokal Female [MeSH]
lokal Aged [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Middle Aged [MeSH]
lokal France [MeSH]
lokal Patient Reported Outcome Measures [MeSH]
lokal Quality-Adjusted Life Years [MeSH]
lokal Male [MeSH]
lokal Quality of Life [MeSH]
lokal Research
lokal Germany [MeSH]
lokal United Kingdom [MeSH]
lokal Psychometrics/instrumentation [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-6057-5920|https://frl.publisso.de/adhoc/uri/dmFuIEJlYmJlciwgSi4=|https://frl.publisso.de/adhoc/uri/U2lkZXktR2liYm9ucywgQy4gSi4=|https://frl.publisso.de/adhoc/uri/VmFsZGVyYXMsIEouIE0u|https://frl.publisso.de/adhoc/uri/TGVwbGVnZSwgQS4=|https://frl.publisso.de/adhoc/uri/Um9zZSwgTS4=|https://frl.publisso.de/adhoc/uri/RmlzY2hlciwgRi4=
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1000 Erstellt am 2023-11-16T06:56:19.163+0100
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