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1000 Titel
  • High prevalence and undertreatment of osteoporosis in elderly patients undergoing total hip arthroplasty
1000 Autor/in
  1. Delsmann, M.M. |
  2. Strahl, A. |
  3. Mühlenfeld, M. |
  4. Jandl, N.M. |
  5. Beil, F.T. |
  6. Ries, C. |
  7. Rolvien, T. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-02-11
1000 Erschienen in
1000 Quellenangabe
  • 32(8):1661-1668
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00198-021-05881-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376703/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • We detected a high prevalence of low bone mineral density assessed by DXA in 268 elderly patients with end-stage osteoarthritis scheduled for total hip arthroplasty (18% osteoporosis, 41% osteopenia). Therefore, and due to the identified concomitant undertreatment, routine DXA measurements should be considered in elderly patients prior to surgery.!##!Introduction!#!Bone quality represents a decisive factor for osseointegration, durability, and complications of an implanted prosthesis. Although the risk of osteoporosis increases with age and the assessment of bone mineral density (BMD) prior to total hip arthroplasty (THA) is recommended in elderly patients, a systematic, unbiased analysis of such patients is not available in the literature.!##!Methods!#!In this retrospective study, we examined 268 elderly patients (age ≥70 years) who underwent dual-energy X-ray absorptiometry (DXA) within 3 months prior to primary THA. Demographics, medical history, radiographic OA grade, and stem fixation method (i.e., cemented or cementless) were obtained.!##!Results!#!In total, 153 (57%) cemented and 115 (43%) cementless stem fixations during THA were performed. Forty-nine patients (18%) were diagnosed with osteoporosis (T-score ≤-2.5), 110 patients (41%) with osteopenia (T-score ≤-1.0), and 109 patients (41%) with normal BMD (T-score >-1.0). Importantly, 36/49 patients (73%) with osteoporosis were not diagnosed before, resulting in a relevant undertreatment. Female sex and low body mass index (BMI) were the main factors negatively influencing the bone mineral density (BMD).!##!Conclusions!#!Due to a high incidence of undiagnosed and untreated osteoporosis in elderly patients with potential effects on the success of osseointegration as well as other clinical outcomes, DXA measurements should be included in the clinical routine for these patients prior to THA.
1000 Sacherschließung
lokal Bone Density [MeSH]
lokal DXA
lokal Female [MeSH]
lokal Aged [MeSH]
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Osteoporosis
lokal Original Article
lokal Osteoporosis/epidemiology [MeSH]
lokal Male [MeSH]
lokal Absorptiometry, Photon [MeSH]
lokal Arthroplasty, Replacement, Hip [MeSH]
lokal Osteoarthritis
lokal Arthroplasty
lokal Bone mineral density
lokal Prevalence [MeSH]
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1000 Erstellt am 2023-11-16T08:17:28.347+0100
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