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1000 Titel
  • Association between sarcopenia, physical performance and falls in patients with rheumatoid arthritis: a 1-year prospective study
1000 Autor/in
  1. Wiegmann, Sabine |
  2. Armbrecht, Gabriele |
  3. Borucki, Diana |
  4. Buehring, Bjoern |
  5. Buttgereit, Frank |
  6. Detzer, Christian |
  7. Schaumburg, Désirée |
  8. Zeiner, Kim Nikola |
  9. Dietzel, Roswitha |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-10-18
1000 Erschienen in
1000 Quellenangabe
  • 22(1):885
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12891-021-04605-x |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524907/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Patients with rheumatoid arthritis (RA) are at increased risk of falls and fractures. Sarcopenia occurs more frequently in RA patients due to the inflammatory processes. Early diagnosis and prevention programmes are essential to avoid serious complications. The present study aims to identify risk factors for falls related to sarcopenia and physical performance.!##!Methods!#!In a 1-year prospective study, a total of 289 patients with RA, ages 24-85 years, were followed using quarterly fall diaries to report falls. At the baseline, medical data such as RA disease duration and Disease Activity Score (DAS28!##!Results!#!A total of 238 subjects with RA completed the 1-year follow-up, 48 (20.2%) experienced at least one fall during the observational period. No association was found between sarcopenia and prospective falls. Age (OR = 1.04, CI 1.01-1.07), HAQ (OR = 1.62, 1.1-2.38), and low FICSIT-4 score (OR = 2.38, 1.13-5.0) showed significant associations with falls.!##!Conclusions!#!In clinical practice, a fall assessment including age, self-reported activities of daily life and a physical performance measure can identify RA patients at risk of falling.!##!Trial registration!#!The study has been registered at the German Clinical Trials Register and the WHO International Clinical Trials Registry Platform (ICTRP) since 16 March 2017 ( DRKS00011873 ).
1000 Sacherschließung
lokal Risk factor
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal HAQ
lokal United States [MeSH]
lokal Hand Strength [MeSH]
lokal Mechanography
lokal Fall
lokal Accidental Falls/prevention
lokal Physical performance
lokal Sarcopenia
lokal Sarcopenia/epidemiology [MeSH]
lokal Arthritis, Rheumatoid/diagnosis [MeSH]
lokal Balance
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal Rheumatoid arthritis
lokal Middle Aged [MeSH]
lokal Arthritis, Rheumatoid/epidemiology [MeSH]
lokal FICSIT
lokal Physical Functional Performance [MeSH]
lokal Research
lokal Young Adult [MeSH]
lokal SPPB
lokal Sarcopenia/diagnosis [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/V2llZ21hbm4sIFNhYmluZQ==|https://frl.publisso.de/adhoc/uri/QXJtYnJlY2h0LCBHYWJyaWVsZQ==|https://frl.publisso.de/adhoc/uri/Qm9ydWNraSwgRGlhbmE=|https://frl.publisso.de/adhoc/uri/QnVlaHJpbmcsIEJqb2Vybg==|https://frl.publisso.de/adhoc/uri/QnV0dGdlcmVpdCwgRnJhbms=|https://frl.publisso.de/adhoc/uri/RGV0emVyLCBDaHJpc3RpYW4=|https://frl.publisso.de/adhoc/uri/U2NoYXVtYnVyZywgRMOpc2lyw6ll|https://frl.publisso.de/adhoc/uri/WmVpbmVyLCBLaW0gTmlrb2xh|https://frl.publisso.de/adhoc/uri/RGlldHplbCwgUm9zd2l0aGE=
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1000 Erstellt am 2023-11-16T11:53:07.731+0100
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