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1000 Titel
  • Impact of surgical site infection on patients’ outcome after fixation of tibial plateau fractures: a retrospective multicenter study
1000 Autor/in
  1. Henkelmann, Ralf |
  2. Glaab, Richard |
  3. Mende, Meinhard |
  4. Ull, Christopher |
  5. Braun, Philipp-Johannes |
  6. Katthagen, Christoph |
  7. Gensior, Tobias J |
  8. Frosch, Karl-Heinz |
  9. Hepp, Pierre |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-06-09
1000 Erschienen in
1000 Quellenangabe
  • 22(1):531
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12891-021-04402-6 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191045/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Surgical site infection (SSI) occurs in 3-10 % of patients with surgically treated tibial plateau fractures. This study aimed to evaluate the impact of SSI on patients' outcome after fixation of tibial plateau fractures.!##!Methods!#!We conducted a retrospective multicenter study in seven participating level I trauma centers between January 2005 and December 2014. All participating centers followed up with patients with SSI. In addition, three centers followed up with patients without SSI as a reference group. Descriptive data and follow-up data with patient-reported outcome scores (Knee Injury and Osteoarthritis Outcome Score [KOOS] and Lysholm knee scoring scale score) were evaluated.!##!Results!#!In summary, 287 patients (41 with SSI and 246 without SSI; average 50.7 years) with an average follow-up of 75.9 ± 35.9 months were included in this study. Patients with SSI had a significantly poorer overall KOOS (KOOS5) (48.7 ± 23.2 versus [vs.] 71.5 ± 23.5; p < 0.001) and Lysholm knee scoring scale score (51.4 ± 24.0 vs. 71.4 ± 23.5; p < 0.001) than patients without SSI. This significant difference was also evident in the KOOS subscores for pain, symptoms, activities of daily living (ADL), and quality of life (QoL). SSI remained an important factor in multivariable models after adjusting for potential confounders. Clinically relevant differences in the KOOS5 and KOOS subscores for symptoms, pain, and ADL were found between those with SSI and without SSI even after adjustment. Furthermore, the number of previous diseases, Arbeitsgemeinschaft für Osteosynthesefragen Foundation (AO) C fractures, and compartment syndrome were found to be additional factors related to poor outcome.!##!Conclusions!#!Compared to previous studies, validated patient-reported outcome scores demonstrated that the impact of SSI in patients with surgically treated tibial plateau fractures is dramatic, in terms of not only pain and symptoms but also in ADL and QoL, compared to that in patients without SSI.
1000 Sacherschließung
lokal Tibial Fractures/surgery [MeSH]
lokal Humans [MeSH]
lokal surgical site infection
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Lysholm knee scoring scale
lokal Tibial Fractures/diagnostic imaging [MeSH]
lokal Epidemiology of musculoskeletal disorders
lokal Fracture Fixation, Internal/adverse effects [MeSH]
lokal Surgical Wound Infection/etiology [MeSH]
lokal Surgical Wound Infection/epidemiology [MeSH]
lokal Outcome tibial plateau fracture
lokal Knee Injury and Osteoarthritis Outcome Score
lokal Quality of Life [MeSH]
lokal Activities of Daily Living [MeSH]
lokal Research Article
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-5274-1896|https://frl.publisso.de/adhoc/uri/R2xhYWIsIFJpY2hhcmQ=|https://frl.publisso.de/adhoc/uri/TWVuZGUsIE1laW5oYXJk|https://frl.publisso.de/adhoc/uri/VWxsLCBDaHJpc3RvcGhlcg==|https://frl.publisso.de/adhoc/uri/QnJhdW4sIFBoaWxpcHAtSm9oYW5uZXM=|https://frl.publisso.de/adhoc/uri/S2F0dGhhZ2VuLCBDaHJpc3RvcGg=|https://frl.publisso.de/adhoc/uri/R2Vuc2lvciwgVG9iaWFzIEo=|https://frl.publisso.de/adhoc/uri/RnJvc2NoLCBLYXJsLUhlaW56|https://frl.publisso.de/adhoc/uri/SGVwcCwgUGllcnJl
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