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1000 Titel
  • Oral health of patients suffering from end-stage solid organ insufficiency prior to solid organ re-transplantation: a retrospective case series study
1000 Autor/in
  1. Moest, Tobias |
  2. Lutz, Rainer |
  3. Jahn, Arne Eric |
  4. Heller, Katharina |
  5. Schiffer, Mario |
  6. Adler, Werner |
  7. Deschner, James |
  8. Weber, Manuel |
  9. Kesting, Marco Rainer |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-10-24
1000 Erschienen in
1000 Quellenangabe
  • 21(1):547
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12903-021-01908-2 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542308/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The oral health of organ transplanted patients before organ re-transplantation is largely unknown. This retrospective clinical study evaluates the necessity for intraoral surgical intervention and/or conservative treatment in candidates awaiting organ re-transplantation, both for graft failure and for reasons of another upcoming solid organ transplantation (renal or non-renal).!##!Methods!#!From January 2015 to March 2020 n = 19 transplant recipients in evaluation on the waiting list for solid organ re-transplantation could be included in the retrospective case series study. Using clinical and radiological examinations, necessity for oral surgical or conservative dental treatment was evaluated. On the basis of anamnesis data, current kidney function, renal replacement treatment (RRT), and medication, a risk profile for several patient subgroups was created.!##!Results!#!The clinical and radiological examinations showed a conservative and/or surgical treatment need in n = 13 cases (68.42%). In n = 7 cases (36.84%) surgical intervention was recommended due to residual root remnants (n = 5), unclear mucosal changes (n = 1), and periimplantitis (n = 1). In n = 16 recipients (84.2%) RRT (n = 15 hemodialysis; n = 1 peritoneal dialysis) had been performed. N = 14 recipients (73.68%) received immunosuppressants. In n = 1 patient (5.3%) displayed intraoral and n = 4 patients (21.1%) extraoral neoplasms due to drug-induced immunosuppression.!##!Conclusions!#!Solid organ transplant recipients with renal failure present a complex treatment profile due to a double burden of uremia plus immunosuppressants. In cases of surgical treatment need a hospitalized setting is recommended, where potentially necessary follow-up care and close cooperation with disciplines of internal medicine is possible in order to avoid surgical and/or internal complications.
1000 Sacherschließung
lokal Organ Transplantation [MeSH]
lokal Pharmaceutical Preparations [MeSH]
lokal Research
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Kidney Transplantation/adverse effects [MeSH]
lokal Immunosuppression
lokal Kidney Failure, Chronic/surgery [MeSH]
lokal Oral Health [MeSH]
lokal Oral health
lokal Organ transplantation
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TW9lc3QsIFRvYmlhcw==|https://frl.publisso.de/adhoc/uri/THV0eiwgUmFpbmVy|https://frl.publisso.de/adhoc/uri/SmFobiwgQXJuZSBFcmlj|https://frl.publisso.de/adhoc/uri/SGVsbGVyLCBLYXRoYXJpbmE=|https://frl.publisso.de/adhoc/uri/U2NoaWZmZXIsIE1hcmlv|https://frl.publisso.de/adhoc/uri/QWRsZXIsIFdlcm5lcg==|https://frl.publisso.de/adhoc/uri/RGVzY2huZXIsIEphbWVz|https://frl.publisso.de/adhoc/uri/V2ViZXIsIE1hbnVlbA==|https://frl.publisso.de/adhoc/uri/S2VzdGluZywgTWFyY28gUmFpbmVy
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1000 Erstellt am 2023-11-16T13:16:21.440+0100
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