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1000 Titel
  • The role of 25-hydroxyvitamin-D3 and vitamin D receptor gene in human periodontal ligament fibroblasts as response to orthodontic compressive strain: an in vitro study
1000 Autor/in
  1. Küchler, Erika Calvano |
  2. Schröder, Agnes |
  3. Teodoro, Vinicius Broska |
  4. Nazet, Ute |
  5. Scariot, Rafaela |
  6. Spanier, Gerrit |
  7. Proff, Peter |
  8. Kirschneck, Christian |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-08-06
1000 Erschienen in
1000 Quellenangabe
  • 21(1):386
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12903-021-01740-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344219/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!This study aimed to investigate, if different physiological concentrations of vitamin D (25(OH)D!##!Methods!#!A pool of hPDL fibroblasts was treated in absence or presence of 25(OH)D!##!Results!#!RANKL, RANKL:OPG ratio, COX-2, IL-6, DHCR7, CYP2R1 and AMDHD1 were differentially expressed during simulated orthodontic compressive strain (p < 0.05). The RANKL:OPG ratio was downregulated by all concentrations (10 ng/ml, 40 ng/ml and 60 ng/ml) of 25(OH)D!##!Conclusions!#!Simulated orthodontic compressive strain and physiological concentrations of 25(OH)D
1000 Sacherschließung
lokal Tooth movement
lokal Fibroblasts [MeSH]
lokal Periodontal Ligament [MeSH]
lokal Research
lokal Humans [MeSH]
lokal Receptors, Calcitriol/genetics [MeSH]
lokal Gene
lokal Vitamin D
lokal Calcifediol [MeSH]
lokal Vitamin D [MeSH]
lokal Polymorphism
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S8O8Y2hsZXIsIEVyaWthIENhbHZhbm8=|https://frl.publisso.de/adhoc/uri/U2NocsO2ZGVyLCBBZ25lcw==|https://frl.publisso.de/adhoc/uri/VGVvZG9ybywgVmluaWNpdXMgQnJvc2th|https://frl.publisso.de/adhoc/uri/TmF6ZXQsIFV0ZQ==|https://frl.publisso.de/adhoc/uri/U2NhcmlvdCwgUmFmYWVsYQ==|https://frl.publisso.de/adhoc/uri/U3BhbmllciwgR2Vycml0|https://frl.publisso.de/adhoc/uri/UHJvZmYsIFBldGVy|https://frl.publisso.de/adhoc/uri/S2lyc2NobmVjaywgQ2hyaXN0aWFu
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1000 Erstellt am 2023-11-16T13:51:39.219+0100
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