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1000 Titel
  • Endoscopic negative pressure therapy as stand-alone treatment for perforated duodenal diverticulum: presentation of two cases
1000 Autor/in
  1. , Doerte |
  2. Jansen, Kai Tobias |
  3. Onken, Flurina |
  4. Stüker, Dietmar |
  5. Zerabruck, Emanuel |
  6. Werner, Christoph R. |
  7. Yurttas, Can |
  8. Thiel, Karolin |
  9. Königsrainer, Alfred |
  10. Quante, Markus |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-11-21
1000 Erschienen in
1000 Quellenangabe
  • 21(1):436
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12876-021-02018-7 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607673/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Endoscopic negative pressure therapy is a novel and successful treatment method for a variety of gastrointestinal leaks. This therapy mode has been frequently described for rectal and esophageal leakages. Duodenal diverticular perforations are rare but life-threatening events. The early diagnosis of duodenal diverticular perforation is often complicated by inconclusive symptoms. This is the first report about endoscopic negative pressure therapy in patients with perforated duodenal diverticula.!##!Case presentation!#!We present two cases of duodenal diverticula perforations treated with endoscopic negative pressure therapy as stand-alone treatment. Start of symptoms varied from one to three days before hospital admission. Early sectional imaging led to the diagnosis of duodenal diverticular perforation. Both patients were treated with endoluminal endoscopic negative pressure therapy with simultaneous feeding option. Three respective changes of the suction device were performed. Both patients were treated with antibiotics and antimycotics during their hospital stay and be discharged from hospital after 20 days.!##!Conclusions!#!This is the first description of successful stand-alone treatment by endoscopic negative pressure therapy in two patients with perforated duodenal diverticulum. We thus strongly recommend to attempt interventional therapy with endoluminal endoscopic negative pressure therapy in patients with duodenal diverticular perforations upfront to surgery.
1000 Sacherschließung
lokal Duodenal Diseases/surgery [MeSH]
lokal Female [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Humans [MeSH]
lokal Intestinal Perforation/etiology [MeSH]
lokal Esophagus [MeSH]
lokal Duodenal diverticulum perforation
lokal Peptic Ulcer Perforation [MeSH]
lokal Endoscopic vacuum therapy
lokal Duodenal Ulcer [MeSH]
lokal Duodenal Diseases/complications [MeSH]
lokal Duodenum [MeSH]
lokal Diverticulum/surgery [MeSH]
lokal Spontaneous duodenal perforation
lokal Diverticulum/complications [MeSH]
lokal Endoscopic negative pressure therapy
lokal Intestinal Perforation/surgery [MeSH]
lokal Case Report
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-8832-5031|https://frl.publisso.de/adhoc/uri/SmFuc2VuLCBLYWkgVG9iaWFz|https://frl.publisso.de/adhoc/uri/T25rZW4sIEZsdXJpbmE=|https://frl.publisso.de/adhoc/uri/U3TDvGtlciwgRGlldG1hcg==|https://frl.publisso.de/adhoc/uri/WmVyYWJydWNrLCBFbWFudWVs|https://frl.publisso.de/adhoc/uri/V2VybmVyLCBDaHJpc3RvcGggUi4=|https://frl.publisso.de/adhoc/uri/WXVydHRhcywgQ2Fu|https://frl.publisso.de/adhoc/uri/VGhpZWwsIEthcm9saW4=|https://frl.publisso.de/adhoc/uri/S8O2bmlnc3JhaW5lciwgQWxmcmVk|https://frl.publisso.de/adhoc/uri/UXVhbnRlLCBNYXJrdXM=
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1000 Erstellt am 2023-11-16T15:29:42.644+0100
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1000 Zuletzt bearbeitet 2023-12-01T02:51:37.939+0100
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