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1000 Titel
  • Placenta accreta spectrum disorders—experience of management in a German tertiary perinatal centre
1000 Autor/in
  1. Bluth, Anja |
  2. Schindelhauer, Axel |
  3. Nitzsche, Katharina |
  4. Wimberger, Pauline |
  5. Birdir, Cahit |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-12-07
1000 Erschienen in
1000 Quellenangabe
  • 303(6):1451-1460
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00404-020-05875-x |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087589/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Placenta accreta spectrum (PAS) disorders can cause major intrapartum haemorrhage. The optimal management approach is not yet defined. We analysed available cases from a tertiary perinatal centre to compare the outcome of different individual management strategies.!##!Methods!#!A monocentric retrospective analysis was performed in patients with clinically confirmed diagnosis of PAS between 07/2012 and 12/2019. Electronic patient and ultrasound databases were examined for perinatal findings, peripartum morbidity including blood loss and management approaches such as (1) vaginal delivery and curettage, (2) caesarean section with placental removal versus left in situ and (3) planned, immediate or delayed hysterectomy.!##!Results!#!46 cases were identified with an incidence of 2.49 per 1000 births. Median diagnosis of placenta accreta (56%), increta (39%) or percreta (4%) was made in 35 weeks of gestation. Prenatal detection rate was 33% for all cases and 78% for placenta increta. 33% showed an association with placenta praevia, 41% with previous caesarean section and 52% with previous curettage. Caesarean section rate was 65% and hysterectomy rate 39%. In 9% of the cases, the placenta primarily remained in situ. 54% of patients required blood transfusion. Blood loss did not differ between cases with versus without prenatal diagnosis (p = 0.327). In known cases, an attempt to remove the placenta did not show impact on blood loss (p = 0.417).!##!Conclusion!#!PAS should be managed in an optimal setting and with a well-coordinated team. Experience with different approaches should be proven in prospective multicentre studies to prepare recommendations for expected and unexpected need for management.
1000 Sacherschließung
lokal Female [MeSH]
lokal Hysterectomy [MeSH]
lokal Placenta Accreta/diagnostic imaging [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Cesarean Section/statistics
lokal Severity of Illness Index [MeSH]
lokal Treatment Outcome [MeSH]
lokal Incidence [MeSH]
lokal Retrospective Studies [MeSH]
lokal Prenatal Care [MeSH]
lokal Caesarean hysterectomy
lokal Germany/epidemiology [MeSH]
lokal Peripartum haemorrhage
lokal Postpartum Hemorrhage/prevention
lokal Maternal-Fetal Medicine
lokal Maternal morbidity
lokal Pregnancy [MeSH]
lokal Placenta Accreta/therapy [MeSH]
lokal Placenta Accreta/epidemiology [MeSH]
lokal Placenta [MeSH]
lokal Placenta accreta spectrum
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-9928-2113|https://frl.publisso.de/adhoc/uri/U2NoaW5kZWxoYXVlciwgQXhlbA==|https://frl.publisso.de/adhoc/uri/Tml0enNjaGUsIEthdGhhcmluYQ==|https://frl.publisso.de/adhoc/uri/V2ltYmVyZ2VyLCBQYXVsaW5l|https://frl.publisso.de/adhoc/uri/QmlyZGlyLCBDYWhpdA==
1000 Hinweis
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1000 Erstellt am 2023-11-16T20:45:46.884+0100
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