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1000 Titel
  • Incidence of concomitant chondral/osteochondral lesions in acute ankle fractures and their effect on clinical outcome: a systematic review and meta-analysis
1000 Autor/in
  1. Darwich, Ali |
  2. Adam, Julia |
  3. Dally, Franz-Joseph |
  4. Hetjens, Svetlana |
  5. Jawhar, Ahmed |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-10-31
1000 Erschienen in
1000 Quellenangabe
  • 141(1):63-74
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00402-020-03647-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8213566/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Introduction!#!Despite successful osteosynthesis, some patients report residual symptoms after ankle fractures. One of the reasons behind the postoperative complaints might be traumatic concomitant chondral lesions (CL) and/or osteochondral lesions (OCL) within the ankle joint. The study aims to systematically review the incidence of CL and/or OCL in ankle fractures and to assess their effect on the clinical outcome.!##!Materials and methods!#!This work was conducted according to PRISMA checklists. A systematic literature search was performed using following keywords: 'Ankle Fractures' OR 'Trimalleolar Fracture' OR 'Bimalleolar Fracture' OR 'Maisonneuve fracture' OR 'Malleolus Fracture' AND 'Cartilage' OR 'Cartilage Diseases' OR 'Cartilage, Articular' OR 'chondral' up to March 2020. The identified articles were analysed to determine the incidence of CL and/or OCL. Included studies in the meta-analysis assessed possible cartilage damage through arthroscopy or MRI immediately after traumatic ankle fractures and described the postoperative clinical outcome.!##!Results!#!The search identified a total of 111 publications; 19 described the incidence of CL and/or OCL after ankle fractures; six met the criteria to be included in the meta-analysis: five (n = 293) diagnosed CL and/or OCL through arthroscopy during ORIF and one study (n = 153) used preoperative MRI. The clinical outcome was evaluated in four studies (n = 177) using AOFAS score and in two (n = 269) using FAOS score. The mean incidence of arthroscopically detected CL and/or OCL was 65 ± 21% [95% CI 53.9 to 76.72]. The cumulative meta-analysis sample size comprised a total of 400 Patients (170 with and 230 without CL and/or OCL) available for a mean follow-up of 23.9 ± 11.5 months [95% CI 11.79 to 36.07]. The average age was 44.3 ± 5.5 years [95% CI 38.57 to 50.13]. The meta-analysis revealed a mean AOFAS score of 91.2 ± 4.8 [95% CI 83.53 to 98.93] with versus 94.4 ± 4.7 [95% CI 86.81 to 102.07] without CL and/or OCL (p = 0.15) and a mean FAOS score of 73.2 ± 11.31 [95% CI - 28.44 to 174.85] with versus 79.0 ± 18.4 [95% CI - 86.77 to 244.87] without CL and/or OCL (p = 0.18).!##!Conclusions!#!CL and/or OCL appear very frequently after ankle fractures. A tendency towards a favourable short- to mid-term clinical outcome was noticed in ankle fractures without CL and/or OCL, however without reaching statistical significance.!##!Level of evidence!#!Level I.
1000 Sacherschließung
lokal Cartilage lesion
lokal Ankle Joint/surgery [MeSH]
lokal Adult [MeSH]
lokal FAOS
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Ankle Fractures/epidemiology [MeSH]
lokal Ankle Fractures/complications [MeSH]
lokal Incidence [MeSH]
lokal Middle Aged [MeSH]
lokal Arthralgia/etiology [MeSH]
lokal Arthroscopy and Sports Medicine
lokal Cartilage Diseases/epidemiology [MeSH]
lokal Incidence
lokal AOFAS
lokal Pain, Postoperative/etiology [MeSH]
lokal Cartilage Diseases/complications [MeSH]
lokal Ankle Fractures/surgery [MeSH]
lokal Ankle fracture
lokal Chondral/osteochondral lesions
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RGFyd2ljaCwgQWxp|https://frl.publisso.de/adhoc/uri/QWRhbSwgSnVsaWE=|https://frl.publisso.de/adhoc/uri/RGFsbHksIEZyYW56LUpvc2VwaA==|https://frl.publisso.de/adhoc/uri/SGV0amVucywgU3ZldGxhbmE=|https://frl.publisso.de/adhoc/uri/SmF3aGFyLCBBaG1lZA==
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